NBME 21 Nuclear/cytoplasmic shuttling: yes;<br />Serine phosphorylation: yes<br />Ubiquitin-mediated proteolysis: no (NBME Answers)

Retired NBME 21 Answers

nbme21/Block 4/Question#4 (reveal difficulty score)
The FOXO transcription factor responds to ...
Nuclear/cytoplasmic shuttling: yes;
Serine phosphorylation: yes
Ubiquitin-mediated proteolysis: no 🔍 / 📺 / 🌳 / 📖
tags: biochem

+13 upvote downvote
submitted by calcium196(12)

The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

bin-mUdtaqitideuei otosrlspyie si ont iyrslbreev aectfdfe by u.iilsnn ehT etuosqin ksas fro reeisvrble swya htat innulsi fcstaef it, nad nuttiubqinaoii dlouw dela ot goerndatdia aiv seesoapt,r hwhci si ton ri.svebrele oiumltNcasraylp/cce tginhuns smeka essne ecaubse XOOF is a initasrpotrnc ota,rfc os it ct’na od sti boj if ti is ni the !smaylcopt

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

meningitis Tkanh you ofr oyur nil!atoaxnpe n O e sue:tinoq wHo atbou het iesnre lrohpip?stonyaoh sI ti easnwedr by puer emnzoiromtai atth eth OOFX FT is reisen hepoohtrdplsay, ro si it a eaglner ctfa that all Ts'F are ioetrrnsee-hnnie phhsadrtlpoeyo? +

tsl19 m'I nto r,eus tub it yam be as psimle sa this: mteueqiuibnaitdid- yolitepsrso is rribivesrlee, tbu hbot CN/ gtihtunls dna ohosyntliopparh are lelreangy seriblrvee serepss.co +

didelphus I salo esusged hatt FXOO mtus eb a ptra fo eth I3KP apwta,hy encsi slninui reltasuge oebsimmatl hutogrh IPK3 dan hte qiusoten tems cisylcpifale sniteomn tat.h ryhohsoaPntliop is a rjoam rpta fo thta tw,pahya os nvee triecdylni nayoprlioosphth wduol ratelueg OXF.O rignarFtstu oeiqus.nt +21

niboonsh s,ye OXOF si aefdtfce dtswamnreo fo het nvaatitico of P.K3I ihsT si a ylrale godo oedvi ttah elsaxinp eth olweh adasecc hoLu?wom3t.dw:h/.ttwvps-wtge/9cs/yb4=cewNua +2

alexb rodAigcnc to kdiaiiwep (.dgniiX/://ewOrFiippo.atti/h1Owkkes) srnloihptyhoapo fo O1XOF si eirielrbevs.r ihTs is renregrfi ot pahhripolytosno of irnese uiedsers on OFXO yb kt,A chihw osrccu ni roenspes to nisnui.l Btu hte BMEN awnsre estsuggs 'tsi eivle.rsebr ahsW't up? +2

almondbreeze ucold wkii eb wnrgo on lrnhpiyopotsoah enbig ie?evrrlesbir agrcondci ot tshi et,racil ti si a eelsvrrbie ceosp:rs irgealtnou of OFox nonstatirprci fsorcta by ebvsrrilee otoylihahposnrp adn iaeotyclnat (c/o0nc.te51e010cs/70m.0c#7ttsl6ese108cpcce/eaphi9w13i/:i84rstnSi/w/dw0riiso me) iwik ifn,o oeevrhw, is uelflph : nI sit -yhpralhstedunpoo ,ttsae OXF1O is zlcladioe ot eth ,culsenu eehwr it nibds ot eth ilsnnui pseeonsr enqcusee otcdela in hte ropremot rof lseogcu ospthasp6eha- nad esreiacns ist tare fo i.inontatprcrs 1OFOX, hgrtuho inarsgcnie sitrnntpiacor fo aup,oge6s-sacpthleo-hs tyldirniec eescsinra het eart fo apcthie loesucg .ot9r1do[upn]ic wHr,eeov ewnh O1OXF is lhoorpehadtyps by Akt on ,h42rT- -r5e,62S and re,3S9-1 it si deeduxlc ofmr hte us,cluen eewrh it is nthe nquiaidtutebi dan rdaededg. heT yhrtoosponaihlp fo OO1XF by Atk eyusbqenustl ceedessra eht taihpec cousgel itnrpdocou tguhorh a esrcedae in rrsoaipnnctti of olgseuc a6hpa.oht-sesp +

leaf_house It esems ielk het oilptyapornhhos omfr tkA dlsea ot udsc,irtneto tbu ameby eth mnsiuspota si thta ahtt ooiaronhhpplsty stpe xecgdnliu( reyev hreot sept fo ouirti-oopitbmseenqu ty)apwah is rere,elvsbi hwere yrolstesoip is f.alin onhn sio@b vdoie si dgoo ubt odnest' tplis isht no.e +

+11 upvote downvote
submitted by ∗imgdoc(183)

The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

sihT tiquoesn is ginska abuto eht niulsni pceerrot iotyrnes nkasei yhptwaa. So kate it rofm eehrt,

hTe ayoppotoihrhlns of het SIR teastvcai a lsagin ntrocitausdn ecasdac hatt aesdl to hte tivaoancti fo herto ksiasne as llew sa rtnnicipasotr straocf ttha eateimd eht alaurlelrtcin cftsfee of uisni.nl pmlCsyNrulceoa/cait htugnistl - eys ber(evrli)es
hrSerTene/noinie sesaink era salo knwno ot erudce eth cvttiayi of .inluins - sey )bre(eeisvlr
qinuibtiU - emdteaid ytreosolisp - no n(to rlvse)eb,eri dna lsoa iunlisn lbioclltmaeya siaerescn roeintp ihssytnse so ti enot'sd hmtca htaw inisnlu dose w.nyaasy

rcocter em if 'Im wo.gnr

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

usmle11a i kitnh ueory torcerc sauce iunutbiqi iddetema opytolesir is na riveesreilbr etps. +1

+7 upvote downvote
submitted by ∗hello(429)

The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

Teh Q tsem satste XFOO is a srtcoptnirina taforc tath edossprn to uilnnsi nnalsggii yb lniagetr the inctprotrsain of lmtacibeo egens -g;-&t ,eroeherft OFXO si a ptnsicnaoirrt ctrofa niveldvo ni lemma.itbso ihTs dhoslu eakm esnse ceesbau tnrer-npuiosecli vcotiatain ash a lreo in lneragiutg iatmlbm.eso

hTsi Q saks bauot ereislbvre ywas htta niusiln tsgereua FOXO natcrrnipost rotfca catv.yiti

iditetUbequdi-inam sipostleyro is evrlisrebrei. ilteianmE lla scoechi cxpeet ofr B, ,D adn H.

sselrrtiI-ucponen nnouitcf ghohutr KIP3 iiglgnsan. PKI3 gliniangs ivsovnle hlrntosopaoihyp fo sneeir g&;--t nriese paosolythnpriho is a besverirle ercosps. ailiEntem H. YFI: /aotnmprnieoi daci oporaphtyolinhs si ylaasw r.vesiebler

uoY rae eftl twih iesccoh B dan .D

OOXF si a tpriatocrisnn tacfor t&--g; atirtsniorcnp crasfot admeite gene atiyvtci yb tnigshltu eetnewb eth aptcslomy dan cunsu.le gugieltnaR eth lncoiota fo OXOF ntcotiiprsarn oatrcf i.(.e ocpslamty .sv cu)nselu wlil refeorhte rvleeirysb mateould meXiOFdtaOd-e bmtieolca egne yvia.ttic

shTi veslea uyo iwth eth eccorrt wasrne: hCcoie B.

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

adong A tebter awy ot tnkih ubaot it is uisnlni sact ouhghrt MAPK ichhw si a iirennnts/oeeerh ekinsa +1

amy I tteaedpertin pymclC/raeuaNcotlis hunsgltit lwduo be eht leturs of sreeni iplyohn,oahpsort so eht ebersvlrei mocnfiadoiit is lnyo no rseine rhtlpoohyonas,ip ichwh laed ot /aimceaclcypntuolrs suhntigtl, tub hte htusltngi eisflt si ton eurnd aifinomIctd.io tog ti .gwonr +

+1 upvote downvote
submitted by ∗usmleuser007(464)

The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

inrSee orhanpsiooyhtpl wlil rcuede isl'usnni tcfsaf.e It tcas on teh nyroseti e.sakin

unscramble the site ⋅ become a member ⋅ ~~$279~~$49

alexandramda 6/lrl:co8r2wtwc9007yd.-/w/sicuef0hS230dp-m0/gtpt80oe.n.l-pf9/b9)(o +

Must-See Comments from nbme21

nosancuck on Absorption atelectasis
assoplasty on Free T4
seagull on GM2
lnsetick on Apocrine
niboonsh on NMDA receptors are blocked by Mg2+ at the ...
drdoom on Deletion of a hydrophobic amino acid ...
hayayah on HCO3− transported in the plasma
mcl on Aortic
notadoctor on Usual interstitial pneumonitis
madojo on Genital herpes
hungrybox on Obstruction of the bile duct
jambo2222 on Lung
hungrybox on Mismatch repair
hungrybox on Hydrochlorothiazide