share email twitter ⋅ join discord whatsapp(2ck)
Free 120  NBME 24  NBME 23  NBME 22  NBME 21  NBME 20  NBME 19  NBME 18  NBME 17  NBME 16  NBME 15  NBME 13 
search for anything NEW!
NBME 21 Answers

nbme21/Block 3/Question#38 (38.0 difficulty score)
A 28-year-old man develops a temperature of ...
Granulocyte colony-stimulating factorπŸ”,πŸ“Ί
tags:

Login to comment/vote.


Tutor box

Members from the Leaderboard offering 1-on-1 help: Want to be listed here? Email us!

 +5 
submitted by yotsubato(1086),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

ehT ptantei has cproteiNuen refve. FSCG lilw teroser his otpirnsuh.le

yotsubato  His RBC and platelets are low, but at acceptable levels for someone undergoing chemotherapy. +22  



 +4 
submitted by rainlad(25),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

lduow we be edriwor uabot sgiun S-FCG eivng taht eh ash cueat ilkemeu?a uodwl ti luatmetsi tgrhow fo ish nccrae ll?ecs

suckitnbme  I think we're assuming that we eradicated the leukemia with the chemo. However at the same time a lot of normal stem cells were also killed off so we give GCSF to help recovery especially since they have an infection. +  



 +1 
submitted by haliburton(217),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

I ocshe GCF-S suecaeb hte gnolrytucsae dsemee to em ermo of a ksir tnah het adteermo emni.aa torrhtpEoieyin emess kile an epoatprripa hicoec as lwel btu SG-CF rome cii.crtal

kentuckyfan  I think it's also because he has an infection (since he was prescribed antibiotics) boosting the immune system is more important than increasing platelet count E) or RBC count A) +5  



 +1 
submitted by anjum(22),

EPO --> RBC's

TPO (romiplostim --> Platelets

G-CSF (filgrastim)--> Myeloblasts (neutrophil, basophil, eosinophil)

INFy --> granulomas

IL-8 --> neutrophil chemotaKxis

As @yotsubato mentioned, pt has neutropenic fever. That is priority for someone undergoing chemo.

djeffs1  I just didn't know which was more important, fixing his low hemoglobin or his leukopenia +