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Retired NBME 21 Answers

nbme21/Block 1/Question#26 (reveal difficulty score)
A 62-year-old man who is a farmer comes to ...
Actinic keratosis ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +8  upvote downvote
submitted by โˆ—sympathetikey(1600)
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The whole "picks at the lesion...causes some bleeding", made me think Psoriasis. Should have gone with Actinic Keratosis based on the patient history (lots of sun exposure).

Actinic Keratosis

Premalignant lesions caused by sun exposure. Small, rough, erythematous or brownish papules or plaques. Risk of squamous cell carcinoma is proportional to degree of epithelial dysplasia.

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thisisfine   Same - the bleeding thing pushed me over to psoriasis as well. Oops. +6
temmy  the distribution of the other lesions, forearm, face, ear, scalp..is not characteristic for psoriasis. +8
hyperfukus  the scalp and ear are actually very common for psoriasis IRL the key is more of the fact that its in areas with UV exposure...actually UV Therapy is found to be helpful in treating some pts w/Psoriasis. Lastly the appearance and lots of things bleed if they were trying to go for auspitz sign it would have tiny dots of bright red blood with slightly touching it +7
hyperfukus  oh last thing psoriasis itches! they said no itching +7
drzed  Those locations may be common IRL, but on step 1, if they want you to think psoriasis, the illness script is going to be someone in their 30s (autoimmune age) with symmetric cutaneous plaques that have a silvery scale on the extensor surfaces. In this case, the age and non-classic description (location, type of lesion) made me steer away from psoriasis. +3
amy  Why not squamous cell carcinoma itself? +
amy  nevermind, I think the 8 year history explained it +



 +6  upvote downvote
submitted by โˆ—niboonsh(409)
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i think of this as ole farmer joe on his actinic farm picking karats (carrots) (actinic keratosis)

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bbr  haha good point +



 +3  upvote downvote
submitted by โˆ—cry2mucheveryday(20)
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i fell for bleeding from lesion at chose psoriasis but psoriasis pts experience itching. Also, the distribution is not characteristic.

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makinallkindzofgainz  Yes it is. These areas are all sun-exposed areas, and he is a farmer. Multiple years of sun-exposure can lead to Actinic Keratosis, a precursor of SCC. +3
mangotango  @makinallkindzofgainz -- I think cry2mucheveryday means "distribution is not characteristic" of psoriasis +1



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