The other comment is partially incorrect. If the drug molecules dissolve in blood, they do not have an anesthetic effect. If they have a low blood solubility, they do NOT dissolve in blood well which leads to a faster anesthetic effect.
The potency is related to the lipid solubility because the drug has to be lipid soluble to cross the blood-brain barrier. A drug with a higher lipid solubility will be able to reach a therapeutic dose in the brain at a lower administered dose, so lower lipid solubility = more potent.
This question asked about a quick induction time, so we want a drug with a low blood solubility so the drug will not dissolve in the blood and will more quickly cross into the brain.
In other terms, a low blood:gas partition coefficient = low blood solubility = short induction time.
As an aside, I strongly disagree with putting this site behind a large paywall given that all of the content on this site is user-generated. The site owner is profiting entirely off of the work of others, and I refuse to support him. I was able to comment without paying for a subscription, otherwise I would have left entirely at this point.
submitted by match95(48), 2019-06-02T23:47:50Z
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