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NBME 18 Answers

nbme18/Block 4/Question#36

18 yo woman given general anesthesia for wisdom tooth extraction

Sarcoplasmic Ca2+ release

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submitted by cbrodo(16),

The patient has malignant hyperthermia, an adverse event associated with some anesthesia drugs (ie succinylcholine). The DOC for treating malignant hyperthermia is Dantrolene, which antagonizes the ryanodine receptor and results in decreased intracellular calcium.