NBME 17 Decreased plasma renin activity (NBME Answers)

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Retired NBME Answer Explanations

Retired NBME 17 Answers

nbme17/Block 0/Question#0 (reveal difficulty score)
A 48-year-old woman comes to the physician ...
Decreased plasma renin activity 🔍 / 📺 / 🌳 / 📖
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submitted by ∗cassdawg(1781)

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This is feedback inhibition of the RAAS (renin-angiotensin-aldosterone system) axis. Increased aldosterone will feedback and inhibit renin secretion of the kidney. (FA2020 p588)

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flapjacks Increased serum sodium concentration is not specific enough to support the diagnosis +11

cheesetouch Fa2018 p332: Hyperaldosteronism - primary hyperaldosteronism seen with adrenal adenoma (Conn syndrome). High aldosterone, low renin. Causes resistant hypertension. +6

mark0polo Serum sodium concentration wouldn't actually change because of the aldosterone escape mechanism in primary hyperaldosteronism +11

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