Leukocyte adhesion deficiency presents with late separation of the umbilical cord, absence of pus (since pus is made of neutrophils), and dysfunctional neutrophils leading to recurrent skin and mucosal infection
LAD is due to a defect in LFA-1 integrin on phagocytes causing deficiency in adhesion and transmigration.
submitted by โcassdawg(1781)
FA2020 p116
Leukocyte adhesion deficiency presents with late separation of the umbilical cord, absence of pus (since pus is made of neutrophils), and dysfunctional neutrophils leading to recurrent skin and mucosal infection
LAD is due to a defect in LFA-1 integrin on phagocytes causing deficiency in adhesion and transmigration.