Clomiphene is a SERM that antagonizes estrogen receptors in the hypothalamus.
If estrogen is antagonized there, there is decreased negative feedback to improve FSH and LH release to stimulate ovulation. This is very important in PCOS and other disorders with decreased fertility.
notyasupremeI guess I wasn't sure because it said FSH and LH levels were normal, so I assumed the problem was with progesterone. But I thought too deep into it and should've just went with my gut.+2
feochromocytomaClopmiphene is usually the answer for infertility with NORMAL anatomy and NORMAL appearing labs+4
sexymexican888Yeah I made the same mistake by choosing progesterone BUT they are used for contraception (pill, IUD etc) and for the PROGESTIN challenge EXCLUDES (if +withdrawl bleed its hormonal PCOS etc) uterine bleeding due to anatomic defects (which will have no withdrawal bleeding i.e asherman)
so as far I know its not used as fertility treatment +
submitted by โbingcentipede(359)
Clomiphene is a SERM that antagonizes estrogen receptors in the hypothalamus.
If estrogen is antagonized there, there is decreased negative feedback to improve FSH and LH release to stimulate ovulation. This is very important in PCOS and other disorders with decreased fertility.