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NBME 15 Answers

nbme15/Block 3/Question#15

A 65-year-old man with hypertension volunteers to ...

Acid-base: Metabolic alkalosis; Volume contraction: yes

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submitted by ergogenic22(123),

Due to "contraction alkalosis" loop diuretics cause volume contraction, thats why you give them.

As a result, there is increase angiotensin II release, increase in Na+/H+ exchange in the PCT (a function of increase angiotensin II), and then increased HCO3- reabsorption, leading to alkalosis