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Retired NBME 15 Answers

nbme15/Block 1/Question#37 (reveal difficulty score)
A 51-year-old woman undergoes dilation and ...
Succinylcholine ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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She has malignant hyperthermia which is a life-threatening complication more common with inhaled anesthetics or succinylcholine (FA2020 p550). Susceptibility is caused by mutations in RYR1 gene encoding for the voltage sensitive calcium channel. The treatment is dantrolene which blocks the release of calcium from the sarcoplasmic reticulum by blocking the ryanodine receptors (RYR).

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