This woman has pulmonary hypertension, likely pulmonary arterial hypertension characterized by increased pulmonary artery pressure with a normal pulmonary capillary wedge pressure (remember pulmonary capillary wedge pressure is associated with left atrial pressure). PAH endothelial dysfunction causes an imbalance in vasoconstrictors (such as endothelin) and vasodilators (NO and prostacyclin). [FA2020 p679]
BosENtan, used to treat PAH, is an ENdothelin antagonist (FA2020 p686)
submitted by โcassdawg(1780)
This woman has pulmonary hypertension, likely pulmonary arterial hypertension characterized by increased pulmonary artery pressure with a normal pulmonary capillary wedge pressure (remember pulmonary capillary wedge pressure is associated with left atrial pressure). PAH endothelial dysfunction causes an imbalance in vasoconstrictors (such as endothelin) and vasodilators (NO and prostacyclin). [FA2020 p679]
BosENtan, used to treat PAH, is an ENdothelin antagonist (FA2020 p686)