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Retired NBME Free 120 Answers

free120/Block 2/Question#17 (reveal difficulty score)
A 6-year-old girl is admitted to the hospital ...
Myeloperoxidase 🔍 / 📺 / 🌳 / 📖
tags: biochem repeat

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submitted by itsalwayslupus(48)
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oFmr omhaPta .hC 2 .gp 4:1 OPM dfceiincey elrstus in civfdetee ovnroscnei of H22O to OlC.H Isardence ikrs orf anddaCi fnxnis lhuhao(tg omst atptenis atiapcm)ms.toy tribulNeo emouttrlzia tset si lmaonr aseecub eth rtrroaeisyp tsurb si yluatcla litsl .atictn ihTs tienpta sah dacidan tfienocin nda y,laedde tub ltlis nac lkil atpsh ,a hcwih lesmneigy oesg onagl thwi het tafc taht the ystoeprirar rutsb is lslti i,acttn tub ttiuhow PMO ti amy be ihrededn a ll.itet

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namesthegame22  eN!ic ,Yes hte TBN etst si nmalor iwht .MODP If it ssy,a A" bnrlioeut rmaulteitoz sett osswh fdeinteci uctierdno by car"tyeslngou = CD!G +

  • Myeloperoxidase deficiency (MPOD) is a common inherited immunodeficiency syndrome characterized by the inability to produce hypochlorous acid within phagolysosomes. The disease is typically mild and may present with recurrent Candida albicans infections.

  • CGD is caused by NADPH oxidase deficiency and results in impaired intracellular killing of pathogens. This presents as recurrent pyogenic infections with catalase+ organisms such as S. aureus with normal concentrations of leukocytes and immunoglobulins.



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submitted by amy(4)
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oS atth is ot yas HTOB GNC(PHDDA iadxseo iy)ecfcndei ADN sdMiepoeyrleao edeinicfyc ipdosrsseep to -iacisvtoaespalte bgu ciif.nento

020AF2 091P lony hezmaipdse no "GDC panttie are ta rindcasee kris for enotncifi by ealatc+as isceeps eaalcbp of nlaeinurztgi ihtre own O2H,2 gnivlea asgyohecpt ithotuw ROS fro igntfigh tfn".iniceo tBu er,ypnptala icdcnorag ot siht snitq,eou stih mttaneste dlhos eurt to Mieeoyrpdesloa iinyfccdee as lwle

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submitted by ilikedmyfirstusername(19)
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yWh ton sreiuepxod udsisem?at sIt hte tpes itrgh ni ebwteen AHNPD ric(hcno omlonagursatu ieaeds)s nad MPO

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ilikedmyfirstusername  I segus ahtt luodc lneatoptyil sftimnae sa na neev woers nehopetyp in ID?CS +1
thekneesofbees  Ist beeucas SOD orsfm 2O2H, tub 2OH2 is okbrne odnw yb aalae.tcs enSic thpSa seruAu si lsatacae o,iptesiv ti 'nowldtu eb dkleil by ti .aaynwy +7
minion7  et@hneeobkfeess ,,,,, so if tpniate sha SOD DECENC,FYII eh ctan eaegertn ,2H20, so he si mcuh mreo etspslueicb ot teg ldleki yb r?onasigm? +1
topgunber  The trfsi ntgih to epek h:agttrsi rtnsaoice in WBCs ear etnam ot eeaiscrn R...OS liehw rosiatenc in orthe ecsll rea to egt dir of ..S.OR usdopierxe is uhmc rrogtesn hnat h2o2 dn(a si thwa w'ere ntisetg wiht het eorpriystar tbrus estt orf H-ACDPNDG xesOadi e.iicd)fynec dSei :nteo DOS ydiecienfc wluod iamfsnet as uol hsireg'g ssdeeai ()LSA ecabeus pduseoeixr si os citxo ti aeadmsg hte slecl eseAsmteh.rteflv SDO krosw on O, ti eaksm 2.H2O oysleaeprMidoex aetsk OH22 dan tsrun it tnoi heblca H-O.C)(l Teh qtsunoie si ygiplnim ttah HBOT adaidnc dan pthsa caonnt be edkill by isth npttei.a hTye are both stlaaeca o-tpviesi sith eamsn that if hte etpinat 'tnac turn 2OH2 tnio het rgesrton -HClO enht the scaaelta soepiivt agssminor acn stuj unrt 2o2h tino awtre nad .nxgyoe opeh atth aemks eness. +3



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submitted by mdmofongo(0)
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eelopsrioydMxae si the nlyo eno ylatcula vdenovil in mnkaig eerf crdas.ail aeaCltsa mkaes 2HO2 otni awtre, oureedSixp meistdsau ietnialsem negyox aadslcri, DLH msaek aatetlc n(o leor ni aatebclri ki),lngli nad NO ,yeahnsts emask N.O

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b1ackcoffee  I totughh DOS alos ocmse o(cse)nd rftea ahaytpw ani(mgk h)2o2 ot ekam ClOH— +1
mdmofongo  woN htat I okto a olok at teh ptawhay agani oyu rea rig.th gKnnowi tish I’d ysa taht reef crliasad fo 2O sltil heav a cchena to ausce semo megaa,d as erewh oHyendrg doepixer ustj evsesr as a aemedntitrie rfo free lcdaari tifo.nroma sThu SOD cyecidifen saelev eosm ardciabtiecl otncia utb PMO vsaele nno?e +2
igurl11  So I msesid sthi oto bc I was golniok orf HANDP Ox (bc I ertertnpedi laeddey otniac taigans athSp A sa ON eeffct no cataesal .)+ ehTn eylfrib serdindeco OPM neht idpekc SDO and dmevo no. utB MPO mksea snsee bc sit ddenee to amke Bealch (who rlptsiouhen lki)l g-;t& feD =;gt& aindCad tfini.ocne htWa yteh maen yb edyal ni avitticy rof hSpat si ktingal atobu hte retax spte deeedn ot sue hte saacrtbei' onw 2H2O ot tehn meak .le.ach.B tuB jstu as het airtabce si kmngai ,O22H ist' sloa imgnoevr it iusgn saeat.acl oS it keta a ttilel ngerol to eahv egnuoh ecalbh to have a tireccbdaial eftcef. +



 -2  upvote downvote
submitted by stunna216(0)
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why si hert efelpyrhirxa dan a aiskinbb gsni gmeanin htta erhet si na MNU s?lioen

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csalib2  ehdsa ,pu i inthk ueor’y ni hte orngw sutienoq raehdt +1



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