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Retired NBME Free 120 Answers

free120/Block 1/Question#15 (reveal difficulty score)
A 40-year-old woman comes to the physician ...
Sertoli-Leydig tumor ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: obgyn

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submitted by โˆ—bwdc(697)
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Leydig cells make testosterone. Leydig cell tumors arenโ€™t always physiological active, but those that are can cause masculinization. Granulosa cell tumors, on the other hand, sometimes produce estrogen (which can lead to precocious puberty in young girls but otherwise may be occult). Teratomas are oddballs that typically have fat, hair, teeth, etc. Thecomas will not be on your test. Ovarian carcinoid is highly unlikely to show up on your test, but if it did, it would likely present with a classic carcinoid syndrome.

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sugaplum  FA 2019 page 632 +2
divakhan  because................"Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen" NBME 24 -#13 Qs explanations/comments on this website, has led me to choose this answer! :D +22
zevvyt  divakhan, thANK you i was hoping praying that someone would have written that +2
meja2  hahaha same!!!! I got this because of the explanations from NBME!! Thanks guyssssss +
meja2  **NBME 24 +



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submitted by โˆ—handsome(3)
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FA 2020 pg 647 states:

Sertoli-Leydig cell tumor - May produce androgens ยŽ virilization (eg, hirsutism, male pattern baldness, clitoral enlargement)

Granulosa cell tumor presents with postmenopausal bleeding, endometrial hyperplasia, sexual precocity (in preadolescents), breast tenderness.

Thecoma - presents as abnormal uterine bleeding in a postmenopausal woman.

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submitted by โˆ—meryen13(48)
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the sketchy on ovarian masses is golden.

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