oYu nac kool at tish eosntiuq egctlta.ilrysa

1. thSruoen lbto -g-t&; so D.NA
2. ythe aer sugin an couenseldaen to arnsfetr btis, isth ne'dost yalelr nema yagnitnh to you y.et
3. DANc si ropnbgi rfo nsgeil mlbuttoaonnin-scigolunm eiorng.

hast'T nro,itmtap aescube onw uyo wnko etyh aer ooignkl ta eth onntctas ronegi of umgilomoinunbl aka Fc fo eht aevyh .aicnh

So hyw is hsti cADN htat nsedeoc cF, giinltgh pu onyl cnoe in thero ,tsessiu but hte maes cNDA ltgshi pu telpuilm mstei in nael 2 n(ebo mrw)oar? shTi is sbcuea,e at hte oebn owrram roadmn rmaobcineitno fo hgtil or veahy hcain ocs,cru adn oru AcND si eepsrtn ni entrifdfe amdrno tanbsomnicoi tihw iglth cnias.h That iecifcsp NcDA qeuncsee tyhe used tn'did caenhg eewnetb hte itesssu ro neev iniwth teh eonb rwm,oar and it lilw oynl dinb ot hte eon egne e.eescnqu heT afct is't igglnith pu mtluiple stmei elslt uyo htta eht ames ucseenqe si psrent,e royu usteqoni si why so naym mi.ste

oAls a esdi ,neto thureons tobsl aer etim giunmsnco, os bals eus eothr tdehmos ot od eth meas gnthi lik(e RCP,) tbu hrtueons btslo rea llist eht estb hnwe it msoec ot ncckghei ioimnluuonlgmb nad T ecll peecrort geen eneegnrarartm.

ihTs neutsqio is ksngia taobu VDJ eeaemnrtanrgr hchwi ehasppn in eht nbeo wr.ramo heT ngsee rea all pdcepho pu aubeecs hte B elcl si gyirnt to raengete a iuuneq bnancitomio rof sti cerprtoe
i elmsp oc.snepc.t. dod ndwoigr

rhtCepa 3 fo hwo" het nimmeu tysems sr"kow - easwmeo book

I ivlbeee lps( eroccrt em if m'I wgno)r you udwlo heva imlasir ruthnSeo botl sltrsue esen ni B llces rneunodgig imstaoc ,toepmtinruyha ubt atth esakt calep in het yordescna pymdolih e,utsis ont in teh beno rrm.owa

I arde hist uoieqsnt as giylnnzaa muionnoiulslgbm in eth neob mworar sv tuo nairilutcgc lierpyhel.rpa I wno reaeliz htsi si nrogw, nda ethy era tujs gnalznayi het DAN fo intefrdef lecl pt,ualopnoi eikl a ceatpehtyo fro elmxpae, tno isnlmoonumublgi renetps ni eht riv.el

With hsti edlcare ,pu I can ees hwo D()VJ nibontamceori dlouc keam the nolriiga DNA eoctisn .hsoerrt tBu woh clodu )(DVJ ibnntoreoimca ypsbisol amek hte DAN cintoes n?lrego eeTrh rae dnbas no het leg ahtt aer hgerhi lmecruaol ehtgiw ni hte boen omrawr. manoeiinboRtc yonl tssernho hte D,NA mseoeno peaesl cocterr m.e

sAlo why is rtehe on adbn in het enob rmowar ttha si het aesm zsie as lriheeaprp ?adnsb ryluSe eth HSCs have tno nuedogner ibi,cntemarono herwe si teihr DN?A??

ngichEo twoesalor@' .ommtecn

ishT Q is nstallesyei gakisn "Wtah is het ninfcotu of nterohSu "l?bsot

:reAwsn Teh ntfncuoi fo Shoeutr boslt si to hckce ofr CBR or TCR neeg rernmeentrasga.

See troslo@aew' oanipantxle for hwta si elflaipccsyi ggnoi no sa fra as yhw eehrt are efitnrfde sdbna ta tdnifefer lsa.epc iAnga, the ersawn ot sith is nge"e rragentraemne" but or@eoaltw sexlnipa ni wiht mroe ei.ltad

urhtnSoe bsotl rea oolcmymn euds ni ionamumlioclg u,tsesid sa eth nurtohse btlo alwslo for eht udtys fo AND sirtoa.teanl Whta si yrmaonll noe gene tifunrcnaogio adtreel ot nmumie lligsoubn ni otms setissu mttssndreoae tuipellm neetiffrd bndas ni hte enbo a,rwmor ieanvitdci of ngee ennramraret.eg siTh si lysiabacl who ew tercae enw sdbaoe.ntii vRtaceie cespsesro era ncooylplal u(tllemip );nabds umalkiee, ni nostatc,r si lcanoloomn gsei(nl adnb.)