need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

NBME 17 Answers

 +11  upvote downvote
submitted by โˆ—lfcdave182(45)
get full access to all contentpick a username

Cold temperature: Causes peripheral vasoconstriction and central vasodilation

  • Increased central blood volume --> Lower ADH due to increased blood volume through kidneys
  • Increased central blood volme --> leads to atrial stretching, increased preload --> Increased ANP release
get full access to all contentpick a username
passplease  what organs are considered "central"? I initially thought that the kidneys would not be getting more blood with most of the blood flow going to the lungs and heart +1
brise  Same :( +
drdoom  the kidneys are the lungs for waste products that can't be expelled via your breathe. (another way of saying this is: the lungs are like the kidneys of your mouth: instead of urinating out of your mouth, you "pee out" CO2 in the form of expired air.) tl;dr the kidneys are very vital organs!! +2
mkayman  my dumbass was like alright you pee in cold water so that means central blood volume is up since you're filtering more blood in the kidneys, ADH is down because you wanna pee and ANP is up because you wanna pee... worked out okay +1



 +2  upvote downvote
submitted by itsgoingtibiaokay(3)
get full access to all contentpick a username

The increased peripheral vasoconstriction due to the body's attempt at heat conservation causes more blood to be shunted to central organs. The more blood that ends up in your central organs (heart, brain, other viscera) causes distention of the the central blood vessels, mainly the heart (remember the heart is actually just one giant blood vessel). When the heart experiences an increase in volume it secretes ANP and BNP, which promote natriuresis by dilating the afferent arteriole. The resulting loss of sodium decreases serum osmolarity and your body compensates by decreasing ADH. This is why you tend to pee in a cold pool.

get full access to all contentpick a username
fatboyslim  Nice explanation! Thank you +
blue4415  In amboss๏ผš Diuresis reflex (Gauer-Henry reflex) Mechanisms of action โ†‘ BP: Atrial stretch receptors inhibit ADH release via afferent vagal fibers โ†’ โ†‘ water excretion by the kidneys โ†“ BP: โ†‘ ADH release โ†’ โ†“ water excretion by the kidneys +



Must-See Comments from nbme17

cassdawg on Membrane lipid peroxidation
cassdawg on Haemophilus influenzae type b
cassdawg on Pelvic Splanchnic
cassdawg on Actinic keratosis
cassdawg on Early septic shock
cassdawg on Epinephrine
flapjacks on Placebo effect
cassdawg on 0.9% Saline
waitingonprometric on Tubular adenoma
bingcentipede on Surface kappa:surface lambda ratio
cassdawg on Free T4
tinyhorse on 25%
cassdawg on Absence of functional LDL receptors in ...
bingcentipede on Residual volume: โ†‘; Arterial PO2: โ†“; ...

search for anything NEW!