You must be logged in to vote!
md_caffeiner
reddit:
Its not about histology knowledge, you just need to know two things about parietal cells - they are eosinophilic on histo and they are located more superficially compared to chief cells (super basophilic, labeled as C). If you know chief cells are C, mucinous glands are A due to the foamy cytoplasm, the answer has to be B.
+
md_caffeiner
reddit2#You're exactly right (although I would say it is histology knowledge). Gastrin stimulates both parietal and chief cells but only parietal cells release hydrogen ions (and chloride ions - to make HCl). ArtiomK is right about the staining and location of parietal cells being highly acidophilic (pink) and predominantly at the apical part of the gastric gland - they're often described as having a fried egg type of appearance (big, round cytoplasm [egg white] with a central, round [yolk] nucleus). Chief cells produce pepsinogen (enzyme) so display the basal basophilic (purple) staining and they're found predominantly at the base of the gastric gland. So, it's a mix of theory and practical understanding - knowing the structure and function of the gastric gland and then the practical histology of the gland (and its cellular composition).
+1
md_caffeiner
dont go to reddit and get distracted for 15 minutes lol
+14
deberawr
it's better than redownloading tiktok and getting distracted for 3 hours lol (don't do what i did its embarrassing)
+
You must be logged in to vote!
tyrionwill
how would I know where is superficial and where is the deep layer?
+
sexymexican888
@tyrionwill if you look at D and E they look more like muscular tissue than glandular tissue (like A,B,C) so thats how you can orient yourself and know that the bottom layer is by D and E so A must be more superficial.
+
You must be logged in to vote!
You must be logged in to vote!
submitted by โbingcentipede(359)
Good explanation on reddit: https://www.reddit.com/r/step1/comments/d8aqj5/spoiler_nbme_16_hey_can_anybody_advice_how_to_get/
Essentially, A = mucinous glands (foamy cytoplasm) B = parietal cells (stain eosinophilc, P ar I etal cells stain PInk w/ a fried egg appearance. Additionally, they're above chief cells C = chief cells (stain basophilic, super dark, and below parietal cells)