Myeloperoxidase deficiency (MPOD) is a common inherited immunodeficiency syndrome characterized by the inability to produce hypochlorous acid within phagolysosomes. The disease is typically mild and may present with recurrent Candida albicans infections.
CGD is caused by NADPH oxidase deficiency and results in impaired intracellular killing of pathogens. This presents as recurrent pyogenic infections with catalase+ organisms such as S. aureus with normal concentrations of leukocytes and immunoglobulins.
oS ahtt is to yas TBOH GA(HCNDPD xeisdoa iyneicd)cfe NDA adolpoeeseryMi ecnyeicdif srsspopeeid to osieectava-lsaipt ubg foecintin.
2A0F02 P901 oyln hiesdzeapm no GCD" ntptaie are ta asnedcire rksi rfo teioincnf yb estl+acaa specise bplacea fo auzngneirtli etihr won 2OH,2 vealgin teaghpysoc tuhotiw SRO rof gingifht ni.iefnct"o utB rneap,ltpay ocargndci to tsih uoet,inqs htsi tmnttesea sodlh ruet to oyedoaeeMpsilr cyenfidcie sa lewl
Why otn iseuodxerp daesim?stu stI eht tspe gihrt ni bwteeen PHAND crni(hoc ganuarosolumt edsi)aes nad POM
Meopoeedylxrsia is teh lyno oen cytalalu vveliond in migkna erfe ldscaria. alaeCsta skmea 2HO2 tion tew,ra ixSrudpeoe aussmidte ieatneimsl yoxneg calrs,iad LDH mekas altteca (on erol ni bialacert ,iinlkg)l and ON ssathy,en saemk N.O
why si tehr ylxpeaehrfir nda a bibikasn gins mnigane thta eethr si na MUN ns?leio
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$279$49ormF htPamao hC. 2 .gp 4:1 MPO ycdcifeeni lruesst ni veedetifc voennciors of 2H2O ot CO.Hl neIdrcesa risk rof Cdianad innsfx lg(aouhht smto tnteipas soma)tiamt.cyp ertbiouNl iteumzotlar etst is nrloma uaecesb eth rporiastrey tsrub is aayllutc ltils .tacint hsiT ptneait has dcnaiad tnionfiec and e,dlyead but lsitl nca illk aptsh a, cihwh miesyglen oegs gnloa hiwt eht fatc ttha hte arprtsyeori rtbus is listl a,ntict btu iwotuht MOP ti aym be enrdeihd a iltte.l
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