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submitted by step420(32), visit this page
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Person has Lambert-Eaton syndrome (hx of lung cancer, and muscle activity that is better with use.

Presynaptic Ca2+ antibodies prevent the release of AcH presynaptically because the antibodies prevent the depolarization within the cell and prevents synaptic vessels of ACh from leaving.

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thotcandy  ugh, I saw Ca2+ and stopped thinking. +18
paperbackwriter  @thotcandy Same here :( +2
sidlersofcattan  they got me too with that Ca++ rip +4
psay1  FA2019 pg. 463 +1
meja2  Lesson learnt: read the answer choices very carefully :( Automatically went for Ca2+ +
chaosawaits  I guess you could call that a Cattrap. I'll see myself out. +1


submitted by thomasalterman(181), visit this page
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The most important hints to the question are as follows, with #2 being the most specific:

1) patient reports pain with overhead motion and reports recurrent overhead motion during work. Overhead motion can damage the supraspinatus muscle due to impingement by the acromion.

2) Pain is worst with internal rotation of the shoulder - this is consistent with the findings of the empty-can test, which indicates a supraspinatus injury.

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mousie  I was thinking along the lines of overhead motion - damage to the subacromial bursa which is between the acromion and the supraspinatus ... also its the most commonly injured rotator cuff m. so could have guessed this one right +2
sympathetikey  Thanks for the explanation. I was scratching my head as to why this is correct, since supraspinatus only does 15 degrees of abduction, but you make a lot of sense. +1
charcot_bouchard  IDK WTF i picked Trapezius +46
ls3076  why would injury to supraspinatus cause weakness with internal rotation though? +9
targetusmle  yeah coz of that i picked subscapularis +3
maddy1994  ya the whole question pointed to supraspinatus ...but last line internal rotation made me pick subscapularis +3
darthskywalker306  I went for Trapezius. That shoulder flexion thing was a big distraction. Silly me. +1
lowyield  saw someone post this on one of the other questions about shoulder... and it works pretty good for this https://www.amboss.com/us/knowledge/Soft_tissue_lesions_of_the_shoulder there's some videos in it, this specific one for the question is the neer test +
psay1  FA2019 pg. 438 +1
hookofhamate  for those who got confused w/ internal rotation - im pretty sure what the last line (pain and weakness with abduction, esp with internal rotation) is describing is the empty can test, which is basically only for supraspinatus injuries because that motion of your arm traps the supraspinatus tendon against the humerus head and causes pain (someone correct me if im wrong pls) but yea, i only figured it out because i had to do the motion with my arm +
zasachwa  For anyone confused about why Supraspinatus since it abducts 0-15, and why Empty/Full can test actually tests the Supraspinatus heres a video: https://www.youtube.com/watch?v=r1bnUcjytXk +
zasachwa  Basically, "internal rotation of the arm decreases the effect of the deltoid muscle on abduction and allows isolated examination of the supraspinatus muscle" +


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