NBME Answers : hpkrazydesi's page

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submitted by joker4eva76(11),

This is representative of leukoplakia, a pre-cancerous lesion of squamous cells. In order for it to spread to distant sites, it must first invade through the basement membrane/submucosa. Could be confused with oral hairy leukoplakia (which also is a white patch that classically arises on the lateral tongue). However, oral hairy leukoplakia is not pre-cancerous and is often associated with EBV infections or people that are severely immunocompromised.

hpkrazydesi How did you know that this wasnt oral hairy leukoplakia? just from the picture? +1

nwinkelmann To piggyback off of @hpkrazydesi, you ruled out oral hairy leukoplakia because the patient was seeing the doctor for normal health maintenance, i.e. not immunocompromised, I'm assuming. +1

dentist @nwinkelmann thats correct! my time to shine. +

submitted by welpdedelp(75),

No diet deficiency, the patient had excess carotene due to his diet

sympathetikey Would never have thought of that. Thanks +2

medschul that's messed up dog +3

hpkrazydesi Excess carotene in what way? sorry if thats a stupid question +

davidw this is directly from Goljan "Dietary β-carotenes and retinol esters are sources of retinol. β-carotenes are converted into retinol. (a) Increased β-carotenes in the diet cause the skin to turn yellow (hypercarotenemia). Sclera remains white, whereas in jaundice the sclera is yellow, which can be used to distinguish the two conditions. (c) Vitamin toxicity does not occur with an increase in serum carotene" +2

davidw β-Carotenes are present in dark-green and yellow vegetables. +

hyperfukus ohhhh hellllll no +

dashou19 When I was a little kid, I like to eat oranges, like I could eat 10 oranges at once, and after a few days, I could tell that I turned yellow... +