NBME Answers : amsizar714's page

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Just as a note for anybody else who was WTF at how 2(29/30)(30/30) = 1/15...a lot of question banks round 29/30 (or any similarly large fraction) out to 1

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gh889 I think you meant 2(29/30)(1/30) just to clarify! +7

niboonsh i am confusion +5

arkmoses You have to use the hardy weinberg formula (1=p^2+2qp+q^2)and p + q = 1 they basically tell you that q^2=1/900 which makes q=1/30 now you can figure out (p=1-q) so p=1-(1/30), p=29/30 then to figure out carrier you solve for 2qp, 2(29/30)(1/30)=1/15 I got it wrong cuz I forgot how to figure out p but hopefully wont happen on the real deal. +5

garibay92 2pq= 2(29/30)(1/30).... Transform this to 2 1 1 2 1 x x = _ = ____ 1 1 30 30 15 +

garibay92 Nevermind :/ It didn't come out as planned :( +

garibay92 /Users/carlosgutierrez/Desktop/IMG_2423.jpg +

pg32 How do we know this disease is autosomal recessive? I assumed it was just because they love these carrier frequency questions with AR diseases, but how do we know it's AR? +

turtlepenlight Sounds like Gaucher (ish?) if i'm remembering correctly +5

ownersucks Niemann Pick disease is characterized by foam cells, which are lipid-laden macrophages. Question stem also mention HSM +

amsizar714 thought this was fanconi anemia +

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Initially i was stuck between embelectomy and fasciotomy, mainly because the pt did seem to have some symptoms of compartment syndrome: pain, pulseless, pallor, perishing cold (remember 6Ps) so i thought maybe fasciotomy could be an answer.

However, fasciotomy is something that would usually occur due to neurovascular compromise, which commonly happens from trauma. So i went with an embolus, since the pt had irregularly irregualr rhythm, prediposing to thrombus/embolus forming, with eventual occlusion.

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abk93 guys, I might be wrong... but I don't think afib EVER gives rise to DVT's... there are these things called capillaries, they are smaller than discrete RBC diameters wide in calliber... a afib producing a clot that is pumped out of the left or right heart will not wind up in the venous circulation... won't happen. am I wrong? +1

abk93 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383153/ +

amsizar714 you right man +