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Retired NBME 23 Answers

nbme23/Block 1/Question#18 (reveal difficulty score)
A 15-year-old boy has nasal polyps and ...
Enzyme B ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem pathways 35

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submitted by โˆ—sajaqua1(607)
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Ezyemn A astnsd ni fro hsosPoeilaphp A2, tingunr slhisppoopidh ni teh elcl bamenemr tino aicdachnior adic.s Fmro eeht,r eymnzE B dtassn rof selxCocyanoeyg XC,(O) iwhle nEmeyz C sndsta ofr s-iLoapgeexy5n O(5.L)- L5O- uopdcser T-5PEH,E wchhi si dernut iotn lkeeouirnts.e ueekoerLnsti plya a ldobue roel ni vneset ilek mtaha,s caeseub heyt ueasc ccbiooncnorrthnitso (nsee ni isth t)naietp dan by gaictn sa eihcmlac atsrcntaatt orf aroinafmytlm e,llsc wehos iactviyt will seolc het iawray rfre.hut yB olibcngk OCX es(uyrblamp with na NA,)SID ew lveae mero of eth rtssebuta ranioicacdh adic fro 5OLX- to mlteuliaty necvrto otni teeoue.ksrlin Tshi si het saisb orf arn,tslntaisamopirnatie-h- wchhi si rnteflqeyu oaidtaessc tihw laans opy.pls mrs(Se'ta )td.ria

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D) nalrsccoPiyt yehsstan . E) mbeanxoroTh tensyhsa

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FA 2019 pg. 475 on aspirin - + NSAID that irreversibly inhibits both COX-1 and COX-1 by covalent acetylation--> decreased synthesis of TXA2 and PG. + S/E: gastric ulceration, tinnitus (CN8), allergic rxn (especially in patients with asthma or nasal polyps). chronic use can lead to AKI, AIN, GI bleeding.


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