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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm micro

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 +12  upvote downvote
submitted by โˆ—et-tu-bromocriptine(140)
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Rleu fo rtm/cuhtsthbou

  • iorneNossu ugfaln neisfco:int rteat iwht a_eclonzo
  • oieurSs anfglu inncstofie (ge, oinoumeiosdcmmmpr nstetpia hiwt ddtiinamesse ni)tnifeoc: ertta whit ietimhnoacrp B

dadiiAontl nofi

  • The niam cseslas of lufannaigt aoistendmic rof slume d:uclein
  • eeslPony (ge, initearcohpm B, ntnystai) - ndBi to egolesrrto meoullces in fagnlu ecll mea,sebrmn etnigrca epsro dan suanigc elcl islsy
  • siearoTlz g(e, loz_neac)o - Peenrvt eht snesshity fo lrotogers,e a ntcoenmop fo nulfga clel enamsbmre
  • iondiasEccnhn (e,g gnap,suofcni ginfac)uimn - nitbihI hte nishsteys fo cng,lua a olhypcdasaceri empconont of algfnu lelc llsaw
  • iyrniiPsmde eg(, )ocnlFestyui - oednCtrev ot ,5if-arorclulu ihwch hnet itibnhsi fluagn ARN nad iotnpre isyentshs
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jcmed  Clel Marbeemn = ictrohAepnim &apm; lnC tisyltaNe WLLA = osugTfn Cpiano otn xim tehm up I yas ot mefsly ITs'" hte FNUIGN ELCL L"LAW +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

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 +5  upvote downvote
submitted by โˆ—hungrybox(1277)
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yM irsmiosnep of petmciAhroni B is ttha 'tsi hte GIB UNGS. tI trsihtag up tsatkca eth sltrseo ni eth uinfg amaslp m.rnmeeab

Mwhineael ill cihbt ursdg klei a-leozs jsut tiibihn tseolr tsieysnhs. (-eiantifnerb X rot,sloenla oszlea- X soeerorlt)g

nuFnsgi X lecl wlal htssisen,y culyifsotne X iuleccn aicd thisns.yse

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et-tu-bromocriptine  leuR fo th:ssmu/nohue ubrcNstrioot ulgnaf ntfiein:cos trtea whti ar oSecnzesuol_oi flguan otfneicni (e,g roimpmdinummcoose ptaitnse wiht etissdndmaei :neof)nciit ttare hwti iitmrhopcean ioAalnddBti Tionf eh nmai lcaesss of inlnuftgaa adcmtnoesii fro lusem nce l:yiudl eosePn g,e( nmehpcoiirta B, n)ystatni - Bdni ot erogolestr uomelslce ni aulgnf ellc ,bnaresmem itegrcan esrpo adn iscganu lelc zss l e oiiyTsrla g(,e )ncozl_oae - trvnePe het syitsesnh of o,tsreolgre a entnompoc of nfaglu llec mbnenecnsrc im iaEhods na ge(, i,sagpnfunco a)niuimnfcg - Ibithin eht hysenists of ,nclaug a yraacpiolcdshe etoncpmno of fanglu ecll alrw sm il diesPnyi eg(, yotcisl)nFue - Ceorvdtne to cufrarl5oli,-u hihwc hetn iinshibt ufangl ARN dna itnrpoe nssheyist +2
et-tu-bromocriptine  ippRpp eht tgoifmat,rn btu elhlfpyuo het eadi gest orscas +
et-tu-bromocriptine  xiFed it, ese o!temnmc +


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