NBME 21 Amphotericin B (NBME Answers)

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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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Reul fo uohhmctbs/ttur

seonuisNro nlfuag ncn:fitisoe teart itwh _zloaonec
Souires nfaulg finsceoitn e,g( umcmrpoiemoniomds atspteni with etemsisniadd nn)e:itfico ttear ithw tiiamhprnceo B

tinidldAoa nfio

Teh amni ascless of ifauntglan soncidemtai fro smuel :nileduc
Psyleone (e,g aeorcptimihn ,B )ynitastn - nidB to loerosgetr eslelcomu in luanfg lelc braesemmn, ianectrg spoer nda ingscua clel yliss
zoeasilTr (g,e l)cnoeaoz_ - eerntvP eth nyeshitss of soelte,rrgo a oncmnetpo of ulfgna cell sneremmba
snihnicEnoacd e(g, acpifsong,nu niagn)fuicm - inhbtiI eht ishetysns of ,clagun a coadialychepsr tpnemoonc fo gnluaf lcel swlla
eidinmPsryi eg(, F)uilceosnty - derovCent ot lfalcuro-,5uri hicwh tneh nibsiiht guafln ARN dan inrptoe ythsnises

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jcmed Clel Mbenamre = cmiopiAerhnt ;ma&p NnCt letlyasi LWAL = iogoasu CTfnnp ton imx emht pu I asy to yfmels sT"'I teh NGUNIF ELCL WLLA" +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

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+5 upvote downvote
submitted by ∗hungrybox(1277)

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yM mpssnieior fo iticpAomnher B is taht i'ts eth GBI SGNU. tI igatsrth pu satctka hte oestrsl in hte gfinu asampl nem.brmea

aihMeewln lli ictbh dgrsu keil -eaozsl tsju inibtih rsolet t.syhiesns aifibnr-(eent X otllonr,sea z-saloe X teeros)ogrl

iFnsung X lcle wall sns,setiyh tnfileyuosc X uecnicl adci istshsey.n

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et-tu-bromocriptine leRu fo rhoN suts/nu:sroimcbohtteu ulafng noi:ftiecsn raett hitw usozreiceo_a nolS gnaufl nfncetoii e,(g modmmornpimsecuoi pstteain hiwt etiisnmsdeda ioniet:ncf) aertt itwh caoehtiinprm dBoAaldtiin oif heTn nmai ascslse fo anfglaiunt imdstnaeoic rof ueslm yl:nlcn ei Pesuoed ,eg( mitihcnopera ,B ntiyt)nas - dBin ot goloesrter lcmloseeu in flnuag clle be,smnmaer catrngei sorep nda gaincus elcl saTller szso iiy eg,( _)nzoaloec - vetrnPe het ssnhsiyet fo roer,leostg a cntmnoeop of funalg cell srhneniocnEb maidmcsane g(,e siapng,oufnc i)fcgnmuina - htbiIni eth ntisysehs fo lug,acn a aceldhapocsiry tncompeon fo flaung clel Pmlasilsiwndirey ,(eg ocse)nFtylui - tenveCrod to olfar,url-5ciu hchwi hten itbniihs uglanf RNA nad niterop eissnstyh +2

et-tu-bromocriptine Ripppp the ftn,ormatig but elyphlufo hte edia steg scasor +

et-tu-bromocriptine exFid ,it ese neommtc! +

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