NBME 21 Amphotericin B (NBME Answers)

NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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leRu fo c/umbsutrtthho

uniosNsroe ulafng inienfcs:to traet itwh e_aoczonl
rsuSoie falngu snieocntif ,(ge mioommmrnecuiospd tniepast thwi nesmiddiates :finnc)eoti eattr thwi omictprneiah B

aiAditndlo ionf

Teh mnia cessals of ungaintfal cndateomsii ofr musle :iendclu
Pnseoeyl (,eg iapceomthnir B, )nttsinya - inBd to oolesgerrt slueomelc ni faungl ecll s,mmeabner cagiernt osepr and icsnuga llec islys
elrTizoas ge,( )elzocn_ao - tePvenr teh snessthiy fo ,rsegotrloe a mcentonop fo fagnul clle nrsbmmeea
iEninccdhonas (,eg ucipo,ngfnas gciufna)mni - intIhib eth ssenhitys fo cn,lagu a clerychisadpoa oopncmtne fo nfgalu lecl lwals
iPireymdsin g,e( clsyneitF)uo - trveenoCd to fial5rlrc,-uou hwcih tneh tihsibin nlufga ANR dna tropeni shtiensys

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jcmed Clle ernMmabe = chtmnioepriA &;amp lletatnysCNi LWAL = nnpoC Tsougifa nto mxi meth pu I ysa ot yfmlse '"TIs eth IUGNFN LELC AL"LW +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

+5 upvote downvote
submitted by ∗hungrybox(1277)

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My ssoenrmiip fo oiecmtripnhA B si tath ist' hte IBG GNUS. tI srgtahti pu ctkstaa the letross in hte fguni apalms bmeranm.e

newhaielM ill htibc gdusr keli sea-loz juts ithniib ersolt y.esishnst -airfienenb(t X taesr,ollno oea-szl X eelorstog)r

ugisFnn X lcel alwl e,ssntyish ylecutsionf X ccneilu dcai eys.sihnts

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et-tu-bromocriptine ueRl of sniums:uhsoetobthrcu /tNor glaufn fc:snieotni teatr hwit nereoc uo_sazSoil faungl ninfoctie (eg, dmpmromsciomounei itaseptn hwit dediasemstin tfnn:ii)coe raett whti haeiitmconpr diA latnidBo Th ifnoe mian aslssce of fnaliunatg ndiiceaotms fro elmus yc sePdnoeun lil :e e(,g hmpaiitcoren B, t)iansnty - niBd ot rgsoolrtee cloemsuel ni fulnag lcle mrnmes,bea raincget poser adn gacisun clel le l si asysiorTz e,(g eac)lz_ono - Petvrne hte stsnysihe fo orloee,sgtr a tmnpnecoo of glunaf cell neonde accrianmsihns m bE g(e, sangncpuof,i )iufginmcan - tiInhib the ssyhnetis fo guanlc, a ircspylehadcao notponemc fo gfualn clel dawieiynimr Plssl (e,g Flysin)touec - ndetvCeor to ifrau,l5-curol iwhch nhte tniisihb nugalf ANR adn npietor syihte sn s +2

et-tu-bromocriptine pRpppi eht intrgat,mfo utb huolyepfl eht adei tseg asosrc +

et-tu-bromocriptine Fxeid ,ti see on!mmcte +

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