NBME 21 Amphotericin B (NBME Answers)

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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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uelR of uthcbm/uttshor

oNrusienos algufn coe:siiftnn treat whit laeczno_o
osiurSe fgauln ineotifcsn e,g( noumciodommipsrme tpteansi hwit deiniesadtsm n)onfi:teic raett tiwh oemaptrhicni B

liAdadtino noif

Teh main ascssle fo gaatnfilnu asmncdieoti rfo uelms ldenciu:
ysPeeoln ,(eg ochrmanpieti B, ta)sniynt - dinB to grlsoereot oslueclme ni uglfan llec eb,rmemnas grtnecia ropes adn icangsu lecl ilssy
ezilrasTo (,eg nacool_)ez - reePnvt het yssnhiest of ge,etorolrs a nentcpomo fo glnafu ecll remsmanbe
hindoEsacinnc eg(, ,fisgnancopu gun)fimacin - tibnhiI teh ethyinsss of uncgla, a oasacpcrheiydl cnoentpmo of gnfual clel llwas
iPnsmidirye ,ge( Foitcsuey)nl - ovrndCeet to 5cuuo,fra-llri whihc ehnt btisniih uglanf NRA dna otpiner esitssyhn

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jcmed lCle nrbmMaee = tmpAhoirneci p;m&a lyCiatnNels t ALWL = ofpaCsio nuTgn ton mix mhet pu I yas to meyslf ITs"' eht FGUNNI CLEL L"ALW +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

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+5 upvote downvote
submitted by ∗hungrybox(1277)

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My rinsepmsoi fo rAopeimtnich B is atht 'its hte BIG GSNU. It titgsrah pu tscakat eth esoslrt ni teh ufgin pasaml e.naerbmm

laeeMnhwi ill cthbi rgsdu iekl osz-eal stuj tiiihbn rteols siynshte.s (tifr-enieban X lntasoe,rol zosa-el X l)osereotrg

nnguiFs X clel lwal i,enshsyts lsctfiyuone X ulcenci ciad .nsiyeshst

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et-tu-bromocriptine luRe of set/:ioutmusnrhrcNuhtobos afnugl fcsi:onenit trate hitw aooelns zi_ouecSr fgunla ctfeiinon ,(eg miimncodopmormeus sieptnat tiwh sdtiieadesmn i:)tonecnfi tetar iwth rehcmiitpnoa adAlidn oBti e oTifnh amin slaescs of nigaafltun mtscaneidio ofr mlsue uieynneloe dlc: sP ,(eg echpatnmrioi B, aynits)tn - dnBi to grerlsoote cmseoluel in fnalgu clle nee,mrbsam itrneagc sopre and nacusig ellc izy oearl issT sl ,ge( zcnl)ao_eo - vtreePn teh hntesssiy fo ,eorsrlgteo a npctemnoo fo gulanf lcle ennisanbmimhEds o nrcec a ,e(g nfs,anuoigcp gfnnmci)uia - nIitbih hte hstsisney fo ulnagc, a lcsyaaohiprdec npceotonm of glnufa clel yii wlassrlnmiP ed eg,( yeuinlcost)F - dtrenoveC to ruuio5acfr-ll, hwcih nthe sitnhbii ugfnal RNA nad oertpni isnse htys +2

et-tu-bromocriptine ppRpip hte r,tantgofim but hlypeolfu hte eaid egts arscos +

et-tu-bromocriptine Fixde it, ese c!nmemot +

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