NBME 21 Amphotericin B (NBME Answers)

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Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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uRle fo sb/hrhuutottmc

essNorioun nuflag stnon:ifcei rteta iwht ocelzoan_
soiSreu gafuln ocniftsein g,(e miemsioocorudmmpn aesinttp thiw idsdietnmaes tf)ei:nnoci ttrae hwit nepirhatcimo B

dAnaltiido info

hTe niam cesslsa of utanafigln adtmeiicons orf ulmes :lcdnieu
lynsoePe g,(e ocniamihtrep ,B tnyt)asni - diBn to lesroeorgt umoelcels in lgufan elcl abe,mnsemr trgncaei srpoe adn uacigns elcl liyss
zaesTroli e,(g cloon_)aez - vePentr teh tinshesys fo rlotogs,eer a ncmenopto fo fgluan lcle sabremnem
ccaisnEonhnid g,e( apgion,nucfs g)nmiuafnci - Ibhitni het inhsessty fo ,lanugc a phslyacdiorace notoncemp of ugnafl clel lalsw
rPienmsiiyd ,g(e )cuneslytiFo - odtrnveeC to a,frui-u5crllo hwcih hten isnibtih flnuga ANR adn prtnioe ehisysstn

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jcmed eCll eMrnbaem = rAophtcniemi map&; nel itlsaCtNy WLLA = annofospuC gTi not mxi hetm pu I yas to sfelym IT"'s het UFGNIN CLEL WL"LA +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

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+5 upvote downvote
submitted by ∗hungrybox(1277)

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yM opsiseirmn fo hnmArctiiope B is taht 'ist the IBG GNSU. It sahtirtg pu taktasc het lrosest in teh gfiun samlap b.amrnmee

Meeihwanl lil bihtc udgsr keli as-zleo juts ihiitbn olerts yshneis.st efnnieb(-itar X arnlt,slooe ealo-zs X ogore)esrlt

gniFuns X lcel wlal sessiyh,nt celunyisfto X cnicleu cadi h.isysents

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et-tu-bromocriptine eulR of m cehssutt/otui:bNhrornuos ulngaf f:tnionsiec retta with sei_coe ualzSnoor aunglf icoinnfte (ge, immdoumoosmipnrce anpttsie tihw dtimnssediae nctoi:nfe)i eartt twih maicorenhpti ldBod iAtnai iTfeh no main lcaesss of tiulanngfa ticdmsneiao ofr umesl leilon:Pyne scude ,eg( ptamonrcehii ,B ns)tianyt - iBdn to gtesolrreo oulcmsele ni naulfg cell mbreasnem, gieanrtc posre dna gusniac ellc lTol i srszsy iae ge(, )z_noaeclo - ertvenP teh snhsisyet of geltro,eosr a otcnpneom of gnaufl lcel ncn irsaE ceanihsodnm mbe ,ge( spnoinaufgc, g)uaincnmif - bhiItni teh sinyehsst fo nclug,a a chaylcadrespoi neoontmpc fo ufnlga clel alPsmr wdy snlieii g,e( yeluciotsnF) - noedtrCev to fci-lr,oruua5l icwhh neht hibntsii fngaul ANR dna petoirn tyess shni +2

et-tu-bromocriptine Rppppi the o,nmittgfar but lpflhueyo het aedi gtse roascs +

et-tu-bromocriptine iFdxe it, ese otn!ecmm +

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