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NBME 24 Answers

nbme24/Block 4/Question#32

A 45-year-old man with hypercholesterolemia (LDL ...

Increased synthesis of LDL receptors

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submitted by m-ice(124),

HMG CoA Reductase inhibitors prevent the liver from synthesizing its own cholesterol. In order to maintain its need for cholesterol, the liver has no choice by to increase its LDL receptor expression in order to take cholesterol from the blood.