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NBME 24 Answers

nbme24/Block 3/Question#1 (19.5 difficulty score)
A 3-year-old girl has a history of recurrent ...
NADPH oxidaseπŸ”

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submitted by m-ice(321),
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et-tu-bromocriptine  To add on: If neutrophils don't have access to NADPH oxidase, they can still use the bacteria's own hydrogen peroxidase to create ROS and kill the bacteria; however, catalase + organisms will not have this hydrogen peroxidase available (because catalase converts hydrogen peroxidase to O2 and water). So then the neutrophils are screwed and have no way of creating ROS. +6  

submitted by faus305(6),

You know why I don't get chronic granulomas? Because I've got NADPH Oxidase. It makes OXYGEN FREE RADICALS THAT WIPE AWAY STAINS.