Why did they ask this same questions twice doe
All anticholesterol agents will upregulate the LDLR one way or another.
Statins, also known as HMG-CoA reductase inhibitors don't forget this doctors should be able to explain such simple concepts like the back of their hand if a patient tries to act smart asking how this drug helps me lose cholesterol.
submitted by โm-ice(370)
HMG CoA reductase inhibitors block the ability of the body to produce its own cholesterol. The liver, unable to make its own cholesterol and still needing to do its job of making lipoproteins, needs to get it from somewhere. So, the liver increases expression of LDL receptors to take more LDL out of the blood for repackaging.