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NBME 23 Answers

nbme23/Block 1/Question#2

A 56-year-old woman comes to the physician for a ...

Microbial oncoprotein that interferes with tumor suppressor proteins

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submitted by lfsuarez(114),

Patient presents with cervical intraepithelial neoplasia, with the most likely culprit being HPV. HPV causes this neoplasia though the creation of E6/E7 oncoproteins which inhibit p53 and Rb tumor suppressor proteins respectively.