NBME 23 Osteogenesis imperfecta, type I (NBME Answers)

Retired NBME 23 Answers

nbme23/Block 2/Question#5 (reveal difficulty score)
A female newborn develops respiratory ...
Osteogenesis imperfecta, type I 🔍 / 📺 / 🌳 / 📖
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+14 upvote downvote
submitted by pizzapack(14)

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oS noce ye'ruo wond to IO dan tscReik itknh otbau the ogsnpteiseah fo eht two saeisdes and ieorgn eht srte fo eht mste rof a n.csedo Bnoe is clbyslaia two pr.tas A iursbof re"b"ar ptra nad a iacmulc e"t"mnec ra.pt OI ahs citeedevf ytep 1 nollcaeg igndlae to obesn that evha on elbompr zrnngmeailii etecm)n( utb rea kciglan eth eabrr. hTis dales ot srpeu ibettrl nbose ttha ekabr lla eht i.etm ieLk nrdsudhe fo rfaesc.tru

iVt D nideeyicfc usecsa an altbiiniy ot iieeamrzln tbu hsa on bpomler twhi aigynl ndow teh elgnloac or ".r"rabe sA a letrus uoy gte ostf dan bneyd snobe. eSur hety can rabke tub the iamn emprbol si lcak fo gtrneht.s

From reeht you kpci IO eaubecs teh kid hsa 0100 ctufre.sra Rkectsi 'uwdtnlo etsnerp htat ay.w

slAo nbuos zordwu:zb traelpapyn "iowrman eacrpapna"e si an aornpmtti aigocdstin elcu fro I.O

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jaramaiha I blveeie o""imranw asw eodtiemnn yb ojlgan in his oauid cete.lrsu +1

veryhungrycaterpillar Vyre inec aolnxtnepai. ishT asw my oligc a,eylctx tbu uyo put it ni rwdos uylufta.lbei +

an1 TULIMELP eutacsrfr in a RNN.EWBO OI bisbae entof hvae ostl of atufcrer niudrg ldeier,yv hits is elinkyul in sietrck from thaw I wokn +

an1 ayok saol rof mose oare,sn I alcrel ttah ni yresg' naotyma, nKerpe nda Aevry dha a abby htiw OI eyt yhet weer hbto n,efi ithw on mfa osythr.i I onkw ti's not cacauert but ti aws a dogo wya to eerrbmem thta DA si the tosm oomcnm tbu ton teh lnoy wya to gte eth ae,ediss eehtr rae stxnieeocp hwhci( BNeM elo.).sv.. I tbe eht sropen that rweot itsh dha lntyceer bdgien on 'yergs ferbeo tniwgri this ioqnteuss msh +1

+9 upvote downvote
submitted by ∗hungrybox(1277)

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:LRTD slaPcihy opsmsytm ;tgt;&g& iflmya yosthri or ithgnany es.le

eiLk the rothe uyg si,ad I gto deapyl rd.ha

I hoh:gtut

• rpoo lrnaapet race

• no flymia ohrtyis

• obne u/eefmsbortcpalrr

nynstIlta enoitpd to Rk.tiesc

T,BU in ecrtrsepto stih si ye:k

• ctsnlaietro tcrntsreioa v(.s acrhciti rorsya → ntrolhcsdcao instehgn)ick

ehr'yeT lscaaibyl tinlgel yuo ot leru otu .ietcskR tI emses 1%00 afniru b/c opor epntaarl acer smeede to elur in tikecR.s ehT on iamylf rotyish esesm ot elur uto O.I

tBu I usges htaw 'veI rladene i,s cphilasy pmytsmos rtpum HNGAYITN LEES no Ns.BEM

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+8 upvote downvote
submitted by ∗seagull(1933)

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The lnnrguydie eanismmhc si yaluusl a lrpbmoe thwi nnivceeoct suitse eud to a lcka of ptey I .enocglal hTis suocrc ni oerm ntah 9%0 fo scsae eud to aminsutto ni het LOC11A or 1O2ALC nge.es hTsee iegctne merolbsp are otenf etrdhneii frmo a 'epsnrso arnpset ni na malouasot anmitond emnanr or ccuor avi a wne itomna.tu

-ikiW

B,lsayacil doog gnf*i** !ckul

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focus iuerctP fo ain"wrmo "beons, sujt rof nu:f ago/tosewo:r2hnoOWw0cio1.g.3epai0m/mt/rtC%oln.0a4adnhwtr2hn-em/vrcra/rWyiwiim2lrcc +2

+2 upvote downvote
submitted by nukie404(8)

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At rsift I wsa itknhnig a!ah ldChi aeu!sb tuB I gssue aimornw nobes are rmeo iseuvgestg of ,IO hhtgaluo eht no yamifl xh rpat saw harret .bleh

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thotcandy eaLltyilr dha it on IO tniul I asw no faimly .xh.. nIst' it OSAATLOUM NDOTNA?MI +3

faus305 FA 1209 pg. 51. Yes it is ulomaasto ma.ndntio ihTs tiqoeusn si pyolor tetnrwi tub het elcsu are m"aonrwi sbeo"n nad ulltmpie ute.rrsfac Petyrt resu eernveyo on sith paeg 'dwoeuvl laeind eth nassdoiig if engies a ealr eitnatp iaednst of nsiug reeht lsnie fo extt ihtw tow nsiht. Qoesnitus elki tish omradsettne ohw thsi sett beacme a yaw fo arningk peoepl bdeas fof fo minaiut yteh wonk dan tno ertih nlcilaic sit.iiebal sTih si hyw setp is spaailsf/ ni 2 aeys.r +

+2 upvote downvote
submitted by ∗azibird(279)

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dWoul istcker seentpr in a enow?nbr hsTi lreaict ceiigbdrsn a seca eesisr says eehr"T ear few ehtro pdlibuseh scaes of connagitle sritkce ucdase by enatraml .D"DV So yebma rseckit uyluals neepsstr tarle ni .file ayoM lcniCi yssa i'st uslulay etraf a"n xrteeme nad pngodeolr itanimv D fdc"ynceii.e

l.ivhnCl:optrb.m/a/c/.i75w/mMgcs/wpnci.27nhe9stP/t4w6 gaoyioy:crs1yc/ika2o4ct0w.s-wseso/s-trolpedntmincss5sa-ttie/ud./sim/e3ci39ns/phwscm

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rongloz isTh swa lteycxa my snageonri of cgishoon eesoenstiOsg rsvsue kisRtec +1

+1 upvote downvote
submitted by ∗lispectedwumbologist(122)

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Hwo is stih eth esrwan fi eehtr is on fiylam rstoihy fo trcererun arrcfe?uts I gtuhoht oneseegsotsi itfrepmcae swa amsolutao dnt?inamo

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seagull !tal!xEcy i'st na asoautolm ndotmiea iseead!s +10

emcee luaomstAo tndoinma iedaesss era ylarvabi sepserx.ive Sl,til I inkht tihs saw a dbayl teniwrt usqtonei huldso( heav venig su omes fiayml isoyt).hr +

wutuwantbruv sAol, FA ssya ahtt cutersarf yam occur durngi the ihnrtigb ers,spoc hwhci si athw I eebliev heyt rewe noggi fo.r I do'nt evbieel hsete nfgisidn lwuod eb nees at ihbtr htiw yna fo eht hroet .seocchi +

d_holles eYha I tthuohg I autrmsdeot MEBN by ngtcsiele Rtkices bc it disa no flyiam ryhstoi ... gseus I tgo dlepay .lol +9

jean_young2019 uldoC it eb a riodapcs e?csas opeSotnunas M tiothsuanTi is a haegnc ni a ngee htat cuocrs uitwhto an biouvos auesc, in a mfaiyl erwhe treeh si on stoihry of eht aprlitaucr gene .matutnio IO si rdetihien sa na uotamlsoa notdniam rt.tia otepilmaAxypr 3%5 of aessc ehva on mayfil oyhstri dan aer laldce ro"si"pacd ssc.ea In crpoaisd escs,a OI is eldeevbi ot lretus fmro a snotepausno enw aoit.utnm alewGifgarPaSps/ytraene.w/he=tsoverstiwreog:gp/m?/.o +6

avocadotoast Aobssm syas eht revsee sptesuyb (espyt I,I )III of OI rea ulalsuy ued ot a new ois)rcdp(a nmtatuoi in 1A1LCO or LO,CA21 hlwie astiptne twih het imdl fmrso (yspte I, IV) ialytyclp evha a rnptae hwit teh i.iodncont +

an1 morf :FA deaucs yb a vtiyrae of egne eecftds s(mto cmomynol A1CLO1 nad AM2L.tsoO 1)C mncoom from is mutlsaaoo n.tmidnoa sThi esndo't mean erteh aer on trohe srf,om ENBM lealry lieks to og orf the aerr areoecunrcsccsuorcnce +

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