NBME 23 Osteogenesis imperfecta, type I (NBME Answers)

Retired NBME 23 Answers

nbme23/Block 2/Question#5 (reveal difficulty score)
A female newborn develops respiratory ...
Osteogenesis imperfecta, type I 🔍 / 📺 / 🌳 / 📖
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+14 upvote downvote
submitted by pizzapack(14)

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So oecn eyruo' dnwo ot IO nad sietcRk nthki buato het topihseagens fo het tow ssiaedse nad ginroe the tser of eth mtse ofr a ndce.os Beno is llabcysia wto sr.pta A fsuoirb re""rba artp nda a camucil "cemt"ne .aptr OI ahs cvtfdeeie ytpe 1 locgalen nigleda ot eobns ttah eahv on ropmbel aigrineiznlm enec)(tm utb ear lciangk hte bearr. sThi aslde ot suepr tltiebr onsbe ttah berak lla the ti.me kiLe deshrndu fo fusarrtc.e

Vit D nfcecyidie sceasu an antlibiyi to enimelazir btu hsa no mlbroep hwit yangil dwon teh leognlac ro "a"re.br As a telrus oyu tge fsot dna dyneb s.beno Seur yeht anc breka ubt the niam lopmebr is calk fo herst.ngt

oFmr ehert oyu cpik IO becaeus het dki sha 0010 ruat.erscf iRsckte nwtudol' tsnpeer ahtt wy.a

losA nosbu zworbdu:z aernlyptap w"nimoar "eacpanepar si na nompitart aigsdintoc elcu ofr .IO

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jaramaiha I blievee rwo"nm"ia aws teiemnnod by agjonl ni sih diauo rlce.utes +1

veryhungrycaterpillar Veyr ecni nx.tapilonea hTsi asw my cogli ct,laexy but uoy utp it ni wodrs uitlle.yfbau +

an1 ILLMTUPE terucsfar ni a WNBOEN.R OI bsiaeb notef ahev otls of crueraft digrnu l,dvyreei isth si ykneillu in ktrecsi rfom atwh I knwo +

an1 yoak lsoa ofr omes se,rona I lercal that ni gy'res m,atoayn eprKen adn ryevA dah a bbay hwit IO ety thye eewr tobh fen,i hiwt on mfa irtyosh. I know 'ist ton taeaccur tub ti wsa a oodg yaw ot merebrem ttha AD is the tmso cmoomn btu otn hte lnoy awy ot tge the sd,eaesi reteh aer escteopnix h(hcwi BNMe o.v.sle).. I tbe teh rospne hatt rowet shit hda eyncletr idgebn no er'syg efbore ntirgwi tshi suoesniqt hms +1

+9 upvote downvote
submitted by ∗hungrybox(1277)

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:RLDT achisylP tsmyopms tggt&;;& mlifya yrtohsi or atnyinhg lees.

Liek the treho uyg id,sa I gto lyeadp a.rdh

I hgth:tuo

• opor napleart rcae

• no afymil tiyshro

• enbo rlu/erbptrcoesfma

nytantslI teinopd to Rtk.cesi

BU,T in ostperetrc this si :eyk

• icealstront cterrntosia (sv. ihcrciat ryasor → lrancoosdthc sen)tinkghic

eyTr'he lbyascila lgetlni ouy to uler tou Riscekt. It esmes 1%00 irfaun cb/ opor aanrtepl crae esdmee ot uelr in teRkics. eTh on ifamly ishotry sesme to lure tuo OI.

Btu I suges hwta e'vI erndeal ,is alhiycps otssmypm mrptu YHIGNNAT ELES on NMB.sE

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+8 upvote downvote
submitted by ∗seagull(1933)

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ehT iergnynldu chimensam is aslyuul a eboplrm wiht civetnocne etusis due to a lkca of etyp I loa.cgnel hsTi ucsrco ni orem than 09% of cseas eud ot uttnaosmi ni hte 1OC1AL ro OC1AL2 n.eseg sThee eeitncg bloserpm aer nefto eerntidhi fomr a 'seposrn prastne in na aumtooasl mdanntio nnaerm or ourcc iva a enw ouitt.nam

iiW-k

s,aBclylia odog *f*i*ng clk!u

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focus ctrPeui of ar"omnwi ,oensb" tujs orf :fun a0misemrCcoinnOhghve2mptlw/%oWa:.0itl./2/rtWadrco0rirtwc4-yweaarion/n3/m.o1g2ohrwc +2

+2 upvote downvote
submitted by nukie404(8)

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tA irtsf I saw innkhitg a!ah dilhC !sbaue But I essgu rmiaown nseob ear oemr esgustivge of O,I ughtahol the no ilaymf hx rtpa wsa rthrea l.bhe

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thotcandy Llyaeltir dha ti no IO nltiu I asw no mayfli .xh.. st'In ti SALOTUAOM AINNTD?OM +3

faus305 FA 0219 gp. .15 Yes it is aolsmuaot nond.mtia ihTs qtueions si orloyp rwttnie tbu eht eclsu rea "ironwma bnoes" and uepllimt ftcsr.arue etPytr suer eoeyrenv on tish pega duwovl'e naldie hte gsidanosi fi eeigns a elra npaitte sidatne of sigun eehrt sinle fo xtet hwit owt ist.nh etQuoissn ekil htis torndeestma hwo isht test mcaebe a yaw fo nakgnir eepplo sbdea fof of uiiatnm yeth onkw nad ont itehr acillcni .ieiltsbia ihTs is why tspe si aslsapi/f ni 2 r.saey +

+2 upvote downvote
submitted by ∗azibird(279)

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Wuodl kecsrti enetpsr ni a r?nbenwo hisT rltiaec nebsigcrdi a aesc reisse ssay e"hTre ear ewf rohte hledupbsi cseas fo igtcolnane sirtekc sceadu yb amrtelna D.V"D oS bmeya iercstk uulsyla penrsest tlrae ni lief. aoyM nClcii yass t'is ulausyl retaf a"n eertxme dna pgrodnloe viminat D cfciy"edni.e

./2Pciwin/nmwpw:ghstt/C.6/M7ib4/s9e.tncaohl7.rvlpc5m/ oc-ny/c/mcyeo2sk3/rp5t/scstds/-twlscasdscwm3o:sa9otwe1neg.r.imyieisuhstioi4pnsai0/-

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rongloz hTsi asw ltcxyae my rinaegosn of isgcnhoo nsOgoeseetsi svrsue iktcesR +1

+1 upvote downvote
submitted by ∗lispectedwumbologist(122)

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oHw is htsi eht nasewr if hreet si on lafiym tyrosih of unrrctere reusactf?r I thouthg geossieonets rtmpifecea was msootaaul inm?odant

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seagull t!c!axEly tis' na tlaamosou amdoiten aesi!eds +10

emcee Astaumool tonanimd isseedas are rbvayail s.seexevirp ,liStl I iktnh tish asw a dably itwtnre uiotsqen lsd(huo ahev ivgen us esom lmyifa )it.hyosr +

wutuwantbruv oA,ls FA ayss that feurrasct may rcuoc rdunig hte ihtnribg s,rceosp hihcw si htwa I ievblee teyh erew noggi rfo. I 'dotn lvieeeb htese isnfdngi doulw be eesn at birht ihwt yan fo hte herot s.ichcoe +

d_holles hYae I thghuto I toarseudtm EMBN by cleisgetn itRkces bc it adis no fiamyl iotysrh ... usesg I tog pdylea .oll +9

jean_young2019 Culdo ti eb a pdoacrsi sec?as poanouSsten TsMniuttoa ih si a caengh ni a nege tath crusco ouhtwit an sioovub ,acuse in a milyfa werhe hteer si no ortishy fo eht rpilacartu egne mi.tatonu IO si ietniderh as na mslotuaoa iadmnont i.atrt yopleaxAmtrip %53 of seasc veah on lyfiam hoirsty adn era aecldl rd""cspaio csae.s In darsipco caes,s IO is lveebied ot uretls omfr a paotsenosnu wne miottn.au fsg./everaotP:s.eweGsg/rol/ahyr=?pmipw/eewtoiSrnagat +6

avocadotoast oAmbss says het vseree tpeuysbs s(pyet ,II )III fo IO era usllauy due ot a new ado(p)csir mtaitnuo ni C1LOA1 ro C1OLA,2 hwiel teiptans itwh teh dilm sorfm (tpyse I, IV) cillyapty evha a rapnte hiwt eht ctiniond.o +

an1 rfom :AF saucde yb a veyrtia of egne tesdefc (otms mnyomocl L1O1CA dan MA1O)t.2LosC omcomn rfom is loasomuat dnnmaiot. isTh es'ntod amne eetrh rae on roeht rsfo,m EBMN elayrl eslki ot og ofr hte arre oceruocceuercarccsnns +

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