wired-inPatient has 5 yr h/o hep C, so it is chronic. Chronic inflammation is characterized by presence of lymphocytes & plasma cells while neutrophils is more characteristic of acute inflammation (Pathoma Ch. 2). AFP is within reference range so probably not HCC. Choice D, palisading lymphocytes & giant cells suggests granuloma which isn't typical of hep C.+51
almondbreezeFa2019 pg 215, 217 on acute/chronic inflammation+2
popofoBut doesn't AFP has not-so-high sensitivity for hepatocellular carcinoma (HCC)? If so, a negative result shouldn't be able to rule out HCC?+1
popofoBut doesn't AFP has not-so-high sensitivity for hepatocellular carcinoma (HCC)? If so, a negative result shouldn't be able to rule out HCC?+1
fatboyslimHCC from hepatitis C usually takes decades to occur. This patient has only had HCV infection for 5 yeats+1
portland2020typically you would have a monocytic inflammatory infiltrate as described. The monocytes are an important component of the innate response. The monocytes can differentiate into macrophages.+
submitted by docred123(9)
Can anyone further explain this?! I could eliminate a few item choices and I guessed correctly, just need more information! Thanks