FA 2019 pg. 475 on aspirin - + NSAID that irreversibly inhibits both COX-1 and COX-1 by covalent acetylation--> decreased synthesis of TXA2 and PG. + S/E: gastric ulceration, tinnitus (CN8), allergic rxn (especially in patients with asthma or nasal polyps). chronic use can lead to AKI, AIN, GI bleeding.
submitted by sajaqua1(462), 2019-06-04T20:55:27Z
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