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Retired NBME 21 Answers

nbme21/Block 4/Question#26 (reveal difficulty score)
The immunosuppressive agent cyclosporin A ...
Interleukin-2 (IL-2) gene transcription ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm Immuno

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 +9  upvote downvote
submitted by โˆ—ihavenolife(81)
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Idk if it helps but I got it using the Hot T-Bone stEAK mnemonic

Hot -> IL 1 (Fever)

T cell stimulation -> IL 2

Bone marrow stimulation -> IL 3

IgE -> IL 4

IgA -> IL 5

aKute phase protein -> IL 6

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temmy  cyclosporine inhibits transcription of IL2 +16
mysticsoul  FA2018 Pg 120 +4
teepot123  same page also for 2019 edition^ +
skonys  2 ILl wheels on my broken Cycle-sporine +



 +3  upvote downvote
submitted by โˆ—hungrybox(1277)
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diagram showing MOA

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 +1  upvote downvote
submitted by โˆ—divya(75)
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Can anyone discuss what's responsible for inhibiting the processes given as other options?

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 +0  upvote downvote
submitted by โˆ—calvin_and_hobbes(2)
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Tacrolimus has the same MOA as cyclosporine

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