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NBME 21 Answers

nbme21/Block 4/Question#9

A 60-year-old woman with psoriasis comes to the ...

Porphyria cutanea tarda

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with PCT you are supposed to avoid excessive sunlight and UV exposure. Methoxsalen makes your skin more susceptible to UV light.

notadoctor  Wouldn't UV light also be contraindicated in Vitiligo? +2  
sweetmed  Phototherapy with photochemotherapy (PUVA) is a well-known and well-studied modality for the treatment of psoriasis, which involves systemic or topical administration of chemicals known as psoralens and administration of ultraviolet light in increasing dosages after requisite time gap. PUVA is also used in the treatment of widespread vitiligo with moderately good results, though it is being surpassed by ultraviolet B (UVB), which is equally or slightly more efficacious with fewer side effects. +4  
dashou19  Honestly, I didn't even know what Methoxsalen is, just chose the right answer because I know you can not give UV light to people with PCT... +2  




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submitted by sweetmed(43),

https://www.ncbi.nlm.nih.gov/pubmed/25382505

PUVA is used to treat Psoriasis and Vitiligo

minion7  puva also used in GVHD +