NBME 21 Antagonizes VLDL-cholesterol secretion (NBME Answers)

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Retired NBME 21 Answers

nbme21/Block 3/Question#13 (reveal difficulty score)
A 40-year-old woman comes to the physician ...
Antagonizes VLDL-cholesterol secretion 🔍 / 📺 / 🌳 / 📖
tags: biochem pharm

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submitted by ∗mcl(671)

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Niacin (vitamin B3) antagonizes VLDL cholesterol secretion

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sbryant6 Fibrates stimulate PPAR-alpha --> LPL upregulation --> decreased triglycerides. However, this question asked about a vitamin. Vitamin B3=niacin. +6

lovebug FA 19, PG 315. Lipid lowering drug bro. +

makingstrides I totally got this question wrong. But I also just realized that it says triglyceride -- VLDL. So VLDL must have been in the answer. Correct me if I'm wrong please. +1

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submitted by medskewl(1)

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I think they are going for Omega 3 (in fish oil) which as seen in the sketchy lowers serum triglycerides by decreasing VLDL and ApoB production

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lba9587 Q stated Vitamin. I don’t believe Omegas 3s are considered vitamins +1

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