need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

Retired NBME 21 Answers

nbme21/Block 3/Question#14 (reveal difficulty score)
A 35-year-old man is brought to the emergency ...
Activation of adenylyl cyclase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: micro repeat

 Login (or register) to see more


 +10  upvote downvote
submitted by โˆ—mcl(671)
get full access to all contentpick a username

Vibrio cholerae is a gram-negative, comma shaped bacteria that can cause watery diarrhea. Cholera toxin functions by activating the Gs proteins --> increasing activity of adenylyl cyclase --> increased cAMP --> increased Na+ and Cl- efflux --> diarrhea.

get full access to all contentpick a username
teepot123  fa 19 pg 146 +
lovebug  Cholerae's exotoxin does not invade mucosa. but just permanently activates Gs according to FA. +
lovebug  Same mechanism[Increase cAMP] : 1) Labile toxin of ETEC, 2) Edema factor of B. anthracis, 3) Pertussis toxin of B. pertusssis +1



Must-See Comments from nbme21

nosancuck on Absorption atelectasis
assoplasty on Free T4
seagull on GM2
lnsetick on Apocrine
niboonsh on NMDA receptors are blocked by Mg2+ at the ...
drdoom on Deletion of a hydrophobic amino acid ...
hayayah on HCO3โˆ’ transported in the plasma
mcl on Aortic
notadoctor on Usual interstitial pneumonitis
madojo on Genital herpes
hungrybox on Obstruction of the bile duct
jambo2222 on Lung
hungrybox on Mismatch repair
hungrybox on Hydrochlorothiazide

search for anything NEW!