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Retired NBME 21 Answers

nbme21/Block 2/Question#36 (reveal difficulty score)
An investigator is conducting a study of ...
Enfuvirtide ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +7  upvote downvote
submitted by โˆ—hungrybox(1277)
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enFUviritide -> used for fusion of HIV virus and target cell

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aishu007  we can also say it enfuviritide blocks entry +
aishu007  of virus into cell +



 +4  upvote downvote
submitted by โˆ—bend_nbme_over(37)
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Didanosine, Lamivudine, and Tenofovir are NRTIs that inhibit nucleotide biding to reverse transcriptase and terminate the DNA chain so those don't affect viral entry. Nevirapine is an NNRTIs that binds to reverse transcriptase and thus also doesn't affect viral entry. Enfuvirtide binds gp41 to inhibit the fusion of HIV and the target cell, thus inhibiting viral entry.

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