NBME 21 Amphotericin B (NBME Answers)

Retired NBME 21 Answers

nbme21/Block 1/Question#38 (reveal difficulty score)
A 47-year-old woman with aplastic anemia is ...
Amphotericin B 🔍 / 📺 / 🌳 / 📖
tags: pharm micro

+12 upvote downvote
submitted by ∗et-tu-bromocriptine(140)

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lReu of hc/sutthmtboru

srsoionNeu ulganf stnnieci:fo ttear ihtw ln_aozoce
oiuSers nagful ifoesnntic (eg, cmimnpsioumoomdre eatsitpn twhi sidnsdemeati i:ectnoni)f rteta thiw nioahmcetirp B

Aaoitidnld foin

Teh nmai sasselc of tnfgilaanu indmateosic for elmsu lcdiun:e
seelnoyP g,(e icomepithnar ,B itannsyt) - Bind ot eorsgrelot musoelcle ni lfagnu lcle msbmeea,nr aitrcgne sorpe dan aucgsin llce issyl
lsioraTze e(g, cez)olano_ - ntPreve hte hysitness of rtoorel,esg a nocmetopn fo nuaglf ellc bamenmres
innscciEdhoan ,g(e fcpoanunis,g gifi)umannc - inIthbi teh iethsssyn of cagnl,u a crayelopacsdhi petnoncmo fo lfguan lelc lawls
Psiryiemdin e,(g )eicntyuFsol - Cnvetrdeo ot 5flluoai,rru-c wcihh tnhe htbnisii lagnuf NAR nda rotepin sshytnesi

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jcmed lCel Mraebemn = inmetAricpoh apm&; eCtsNtllay in LLWA = ansoTunpigofC not xim temh up I say to symfel sI'T" hte GNNIUF LECL LWAL" +3

Terbinafine/Tolnaftate - inhibit squalene epoxidase/sterol biosynthesis. Squalene builds interfere with fungal membrane function and cell wall synthesis.

+4/- h0odtime(54)

+5 upvote downvote
submitted by ∗hungrybox(1277)

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My reonipsism of cteAirnhiomp B si taht s'it teh BIG GSUN. It srtigtha up tacksta eth slestor in the ifgnu asmapl emnbr.ema

wnehleiMa lli tihbc sdugr kiel az-lose ustj ihbtnii eslrto t.hsessniy -aeini(rntbef X ln,lseortao -elszao X g)toolresre

giFsunn X clle llwa s,sinthyse iflnceysuto X enluicc idac .shssetiny

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et-tu-bromocriptine ueRl fo r omutubtn:ssho/rhoNcutesi gnulaf :enicfnstio etart tiwh _iae lsncruooSoez flngau oneinctif ,e(g niuspmroiooecdmmm etniptsa htwi dssiemdeatni fnetiino)c: trtae ihtw pcmhaoirtine ddAaiBlti no fToin he mian leasscs fo fuanailtng teodscianmi rfo sumle ei:udo lcenly nsP e eg(, taciienphomr ,B ytns)ntia - inBd ot etelrogsro moulseelc in lufagn clle me,abrsnem tingeacr peors dna sganciu cell liea sl sizos Tyr ,g(e la_ce)onoz - venetPr teh sshstneyi fo resrt,ooegl a nnpteocom of fnalug ecll s einoeiahasncE ncdbrnmm ,eg( ofnpuga,icsn in)faigunmc - iinbtIh teh nehyissst of alngu,c a lpyraehdasicoc tmepoocnn fo lnguaf lelc aslind wPlsyeir mi (,ge e)uslFoiyctn - otnrdvCee ot u,5uloca-lrirf wihch thne thnsiiib glnuaf ANR nda otirenp e issy ntsh +2

et-tu-bromocriptine iRpppp teh ir,mogntfat btu lpufeolyh het aide tgse ssraco +

et-tu-bromocriptine xeFid t,i ees oenct!mm +

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