Ezetimibe is the dyslipidemia drug that blocks 1st step in cholesteral metabolism - absorption. It prevents cholesterol absorption at small intestine brush border.
Cholestyramine: prevents bile acid reabsorption, forcing new cholesterol synthesis
Fibrates (gemfibrozil): activates LPL, PPARa
Niacin: inhibits lipolysis
Statins (simvastatin): inhibits Hmg-coA reducatse to reduce cholesterol synthesis.
submitted by โbingcentipede(359)
Ezetimibe is the dyslipidemia drug that blocks 1st step in cholesteral metabolism - absorption. It prevents cholesterol absorption at small intestine brush border.
Cholestyramine: prevents bile acid reabsorption, forcing new cholesterol synthesis Fibrates (gemfibrozil): activates LPL, PPARa Niacin: inhibits lipolysis Statins (simvastatin): inhibits Hmg-coA reducatse to reduce cholesterol synthesis.