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Retired NBME 17 Answers

nbme17/Block 1/Question#44 (reveal difficulty score)
A 41-year-old man with asthma and an allergy ...
Albuterol ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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Albuterol: short-acting beta agonist (activates B2 causing bronchodilation), used during acute exacerbation.

Beclomethasone: Inhaled corticosteroid (inhibit the synthesis of virtually all cytokines), 1st line therapy for chronic asthma.

Cromolyn sodium: Mast cell stabilizer (prevent the release of inflammatory mediators from mast cells), used for prevention of bronchospasm, not acute bronchodilation. Rarely used.

Diphenhydramine: Reversible Histamine-1 blocker, used for allergy, motion sickness, sleep aid.

Zafirlukast: Antileukotriene (block leukotriene receptors CysLT1. Especially good for aspirin-induced and excercise-induced asthma.



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