Also, estrogen increases cholesterol production. Adipose tissue has aromatase to convert steroids to estrogens. Estrogens stimulate HMG-CoA reductase to increase cholesterol production. Thus "fat" person has increased production of estrogen-> increased endogenous cholesterol
submitted by โcassdawg(1780)
Fat, fourties, female is at increased risk for gallstones because of her liver increasing cholesterol synthesis. (FA2020 p396)