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NBME 17 Answers

nbme17/Block 0/Question#0 (reveal difficulty score)
An investigator is studying mechanisms of ...
Transforming growth factor-beta ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1780)
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The key here is "wound healing". TGF-beta is a vital cytokine in the healing process as well as in attenuation of immune response (FA2020 p216)

FGF, TGF-beta, VEGF, PDGF, EGF (all GROWTH factors ending in GF which promote healing) as well as metalloproteinases (for remodeling) are vital in the wound healing process.

TGF-beta and IL-10 are the two "resolution" cytokines vital in attenuating the immune response. FA2020 p108 has important cytokines.

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