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NBME 17 Answers

nbme17/Block 0/Question#0 (reveal difficulty score)
63-year-old man, 3-month history of ...
Increased capillary hydrostatic pressure ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1780)
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Sleeps better sitting upright - left heart failure symptoms

JVD and anke edema - right heart failure symptoms

Right heart failure with backup into the venous system causes edema by increasing capillary hydrostatic pressure (the push pressure) and "pushing" more fluid into the interstitial tissue space.

Decreased plasma colloid oncotic pressure (the pull pressure) could technically also cause edema but this would be likely more associated with a history of symptoms of loss of protein (i.e. liver failure and inability to make albumin or kidney issues and proteinuria).

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waitingonprometric  I think given the symptoms of orthopnea, he has L side heart failure with fluid backing up into his lungs. L sided heart failure is the most common cause of R heart failure, which is likely present in this dude too (increased JVP). Along with L heart failure, you would get decreased CO --> activation of SNS and RAAS to maintain blood pressure --> increased fluid retention/volume in circulation --> increased capillary hydrostatic pressure --> third spacing of fluids (i.e. ankle edema). +6
kayla  Please correct me if I am wrong, but I also believe here they are testing about transudative vs. exudative. Heart failure is transudative thus, we can exclude any answer choices regarding capillary permeability. As cassdawg stated, there is no indication here of any loss of protein, so we can exclude the oncotic pressure as a reasonable answer choices, and what we are left with are the hydrostatic pressure. The only one that makes sense between the two is an increase in hydrostatic pressure.Also waitingonprometric, love the name, story of my life! +1



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