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Retired NBME 17 Answers

nbme17/Block 3/Question#27 (reveal difficulty score)
A 44-year-old woman comes to the physician ...
Ubiquitin ligase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biochem pathoma

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submitted by โˆ—cassdawg(1781)
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A primary means of protein degradation within the cell is ubiquitination of proteins which targets them for degradation by the proteosome. (see image)

E6 hijacks this system and causes ubiquitination of p53 (see image)

Basically if there is a question about degradation of a protein in the cell its likely through ubiquitination.

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