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NBME 16 Answers

nbme16/Block 1/Question#48 (4.3 difficulty score)
A newborn female is diagnosed with ...
Thyroxine (T4)🔍

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In other words, what is the active product of the thyroid gland that is needed for normal development? Only thyroxine, iodine and thyroglobulin are in the thyroid gland. Of these, thyroxine is the active hormone produced that would affect development.

Sounds like a negative feedback question. If T4 crosses the placenta, it basically inhibits TSH release. Then the newborn won't be making TSH, so this could be like a transient hypothyroidism