Vinca alkaloids (e.g. vincristine, vinblastine) inhibit microtubule production and mitotic spindle assembly. They bind Beta-Tubulin and inhibit its polymerization into microtubules, arresting dividing cells in the M-phase of mitosis. FA 2019 p. 433.
submitted by โbaja_blast(219)
Vinca alkaloids (e.g. vincristine, vinblastine) inhibit microtubule production and mitotic spindle assembly. They bind Beta-Tubulin and inhibit its polymerization into microtubules, arresting dividing cells in the M-phase of mitosis. FA 2019 p. 433.