DMD->Deleted dystrophin, Dystrophin helps anchor muscle fibers, primarily in skeletal and cardiac muscle. It connects the intracellular cytoskeleton(actin) to transmembrane proteins ฮฑ and ฮฒ-dystroglycan, which are connected to the extracellular matrix.
submitted by โergogenic22(401)
Classic picture for Duchenne muscular dystrophy. which is due to deleted dystrophin protein.
From FA: "Dystrophin helps anchor muscle fibers, primarily in skeletal and cardiac muscle. It connects the intracellular cytoskeleton (actin) to the transmembrane proteins ฮฑ- and ฮฒ-dystroglycan, which are connected to the extracellular matrix (ECM)"