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NBME 13 Answers

nbme13/Block 3/Question#31 (3.3 difficulty score)
A 23-year-old woman with type 1 diabetes ...
Inability to produce hydroxy-halide radicals🔍
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submitted by jsmoov(1),

Halides are the elements in the 2nd the last column of the periodic table (F, Cl, Br, I, etc). Defective MPO prevents conversion of H2O2 into HOCl (a hydroxy-halide) which is aka bleach and the most powerful antimicrobial our phagocytes can synthesize