2,3-BPG created in RBCs during glycolysis. The production of 2,3-BPG is increased when oxygen availability is reduced, as occurs in chronic lung disease, HF& chronic exposure to high altitudes. Elevated levels of 2,3-BPG decrease Hb O2 affinity, allowing the release of more O2 in the peripheral tissue
to snoo-finity ... and beyond!
submitted by huyhoa1qh(0), 2019-10-20T23:53:58Z
2,3-BPG created in RBCs during glycolysis. The production of 2,3-BPG is increased when oxygen availability is reduced, as occurs in chronic lung disease, HF& chronic exposure to high altitudes. Elevated levels of 2,3-BPG decrease Hb O2 affinity, allowing the release of more O2 in the peripheral tissue