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Retired NBME Free 120 Answers

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submitted by โˆ—topgunber(68)
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Hep C - RNA virus (not enveloped) (picorna family + ssRNA).

Viruses are intracellular- so their products are displayed on MHCI molecules (using tap1/tap2 to shuttle the viral proteins broken down by proteosome) and are shipped to the cell surface of infected cells. Since this is MHC I we know CD8+ t cells (cytotoxic T lymphocytes) are responsible for attacking the infected cells.

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helppls  Would the self peptides be an auto-immune response? (autoimmune can be cause by either CD8 or CD4 correct?) +



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