NBME Answers : mannywillsee's page

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submitted by hungrybox(1277), visit this page

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HIGH YIELD: "nonbilous vomiting" means that the issue/obstruction comes before (proximal to) the second duodenum, where bile is released.

At around ~4 weeks (give or take a few) is when pyloric stenosis usually shows up.

ez pts for u now keep it up

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mannywillsee Sadly the easiest question that just jumped out of its way and said Pick me! +

submitted by vlodkadrinker(7), visit this page

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tinidazole preferred due to single dose

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sweetmed or metronidazole +

niboonsh what would his diagnosis be tho? +

lostweightthxnorovirus @niboonsh Giardia I believe. the trophozoite is pictured in the problem and has a classic "shield-like" appearance. FA 2019 pg. 155 has more information and the sketchy for it was really good! +1

nwinkelmann Per FA, DOC for giardia = metronidazole. MOA of metronidazole = formation of toxic free radical metabolites in the bacterial cell wall that damage DNA making it bactericidal and antiprotozoal. Metro treats = GET GAP = giardia, entamoeba, trichomonas, Gardnerella, anaerobes (below diaphragm), and H. pylori (as an alternative to amoxicillin in PCN allergy). Adverse effects = disulfiram-like reaction, HA, and metallic taste. I didn't know what Tinidazole is, and found out it is of the same drug class as Metronidazole, so makes sense why it would also be used for Giardia. For the purpose of the UMSLE 1, though, I think metronidazole would be DOC (especially because tinidazole isn't in FA). +10

mannywillsee This little bug has has a face, and now you can't unsee it either! +

submitted by mcl(671), visit this page

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Labeled CXR showing position of different valves.

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hyperfukus this link is great! they're still kind of close together :( its so hard to tell for me w/o reference of the others +

mannywillsee So the way to differentiate Aortic valve from the others is by checking the lateral view, AV will be more medial than both tricuspid and mitral; tricuspid will be more anterior and mitral will be posterior while Pulmonary is doing its own thing +3

sunnyside A surgeon told me once that there is no "left" and "right" heart - only anterior and posterior - referring to how the heart sits in vivo. Helps me think through imaging and these weird anatomy questions +1

sunnyside Just to finish out that thought... Right side = anterior. Left side = posterior. +

submitted by neonem(630), visit this page

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Morphine is a mu opioid agonist - one adverse effect of opioids is mast cell degranulation that is IgE-independent. Release of histamine is akin to an anaphylactic reaction --> pruritis, etc.

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sympathetikey Never had heard of that one. Just a good guess. Thanks! +

yb_26 IgE-independent mast cell degranulation can also be caused by radiocontrast agents, some antibiotics (vancomycin) +8

temmy it was a u world question +

mambaforstep FA 2019 pg 400 +1

mannywillsee i'm in FA 2019 and pg 400 is blood groups and hemolytic diseases of the newborn. I found this info in page 535 +

mannywillsee i'm in FA 2019 and pg 400 is blood groups and hemolytic diseases of the newborn. I found this info in page 535 +1

mambaforstep under mast cells "IgE-independent mast cell degran"! FA 2019 pg 400 +

mumenrider4ever Uworld QID 11852 talks about this Also FA 2020 pg. 408 (under mast cells) +

submitted by neonem(630), visit this page

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Morphine is a mu opioid agonist - one adverse effect of opioids is mast cell degranulation that is IgE-independent. Release of histamine is akin to an anaphylactic reaction --> pruritis, etc.

get full access to all content ⋅ become a member

sympathetikey Never had heard of that one. Just a good guess. Thanks! +

yb_26 IgE-independent mast cell degranulation can also be caused by radiocontrast agents, some antibiotics (vancomycin) +8

temmy it was a u world question +

mambaforstep FA 2019 pg 400 +1

mannywillsee i'm in FA 2019 and pg 400 is blood groups and hemolytic diseases of the newborn. I found this info in page 535 +

mannywillsee i'm in FA 2019 and pg 400 is blood groups and hemolytic diseases of the newborn. I found this info in page 535 +1

mambaforstep under mast cells "IgE-independent mast cell degran"! FA 2019 pg 400 +

mumenrider4ever Uworld QID 11852 talks about this Also FA 2020 pg. 408 (under mast cells) +