NBME Answers : loaloagubba's page

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Streptococcus Pyogens (group A strep) has a superantigen causing shock. This antigen Erythrogenic Exotoxin A causes a Toxic shock-like syndrome: Fever, Rash, Shock, Scarlet Fever.

FA pg 133 (2019)

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extraordinr correction: GAS erythrogenic toxin causes scarlet fever specifically in this question there is no reason for this child to have TSS +6

loaloagubba SpeA and SpeC toxin is erythrogenic toxin referred to here. +4

baja_blast Erythrogenic exotoxin A + Strep Pyogenes is responsible for BOTH Scarlet Fever and Toxic Shock Like Syndrome. It can also cause Necrotizing Fasciitis. It's definitely Scarlet Fever in this question but I just don't want people to get confused. FA2019 pages 133, 136 +

baja_blast Sorry, not A. Just Erythrogenic Exotoxin +. +

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Why not clinical trial? They could report a rare adverse effect in phase 4 clinical trial right?

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sunshinesweetheart there's no control group. it's just a case study. x3 +3

sunshinesweetheart plus clinical trials at that stage would have had tons and tons of participants (and, most importantly to rule out all the answers, control group) +1

servage I totally thought it was phase 4 of a clinical trial as part of post-market surveillance. Smh. +3

loaloagubba For phase 4 they report to the said findinds and adverse to the FDA via a portal not to a journal. +1